Evidence map›Paper›PMID 28055249›Full record

ArticleThe British journal of radiology2017

Volumetry of the dominant intraprostatic tumour lesion: intersequence and interobserver differences on multiparametric MRI.

Hugh Harvey, Matthew R Orton, Veronica A Morgan, Chris Parker, David Dearnaley, Cyril Fisher, Nandita M deSouza

Abstract read
In one paragraph

Article in The British journal of radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hugh Harvey1 Cancer Research UK Imaging Centre, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK.
Matthew R Orton1 Cancer Research UK Imaging Centre, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK.
Veronica A Morgan1 Cancer Research UK Imaging Centre, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK.
Chris Parker2 Academic Urology Unit, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK.
David Dearnaley2 Academic Urology Unit, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK.
Cyril Fisher3 Department of Histopathology, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK.
Nandita M deSouza1 Cancer Research UK Imaging Centre, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, UK.

Funding

Cancer Research UK 10588Cancer Research UK 12518Cancer Research UK 16464Cancer Research UK 19727Medical Research Council G0701533
6 · The paper itself

Abstract

objectiveTo establish the interobserver reproducibility of tumour volumetry on individual multiparametric (mp) prostate MRI sequences, validate measurements with histology and determine whether functional to morphological volume ratios reflect Gleason score.

methods41 males with prostate cancer treated with prostatectomy (Cohort 1) or radical radiotherapy (Cohort 2), who had pre-treatment mpMRI [T

resultsLimits of agreement of DIPL volumes between observers were: T2W MRI 0.9, -1.1 cm

conclusionThe low variability of the DIPL volume on T2W MRI between Observers and agreement with histology indicates its suitability for delineation of gross tumour volume for radiotherapy planning. The volume of cellular tumour represented by DW-MRI is greater than the vascular (DCE) abnormality; ratios of both to T2W volume are independent of Gleason score. Advances in knowledge: (1) Manual volume measurement of tumour is reproducible within 1 cm

Indexed as

AgedContrast MediaDiffusion Magnetic Resonance ImagingHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleNeoplasm GradingObserver VariationProstateProstatic NeoplasmsReproducibility of ResultsRetrospective StudiesTumor BurdenContrast Media

Identifiers

PMID28055249
PMCPMC5601508

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.