Evidence map›Paper›PMID 28055228›Full record

ArticleBrain injury2017

Preliminary investigation of Brain Network Activation (BNA) and its clinical utility in sport-related concussion.

A Reches, J Kutcher, R J Elbin, H Or-Ly, B Sadeh, J Greer, D J McAllister, A Geva, A P Kontos

Open access · bronzeAbstract read
In one paragraph

Article in Brain injury, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. In-clinic event related potentials after sports concussion: A 4-year study.Journal of pediatric rehabilitation medicine · 2020
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

A Rechesa ElMindA Ltd , Herzliya , Israel.
J Kutcherb The Sports Neurology Clinic , University of Michigan , Ann Arbor , MI , USA.
R J Elbinc Department of Health, Human Performance and Recreation , University of Arkansas , Fayetteville , AR , USA.
H Or-Lya ElMindA Ltd , Herzliya , Israel.
B Sadeha ElMindA Ltd , Herzliya , Israel.
J Greerb The Sports Neurology Clinic , University of Michigan , Ann Arbor , MI , USA.
D J McAllisterd UPMC Sports Medicine Concussion Program, Department of Orthopaedic Surgery , University of Pittsburgh , Pittsburgh , PA , USA.
A Gevaa ElMindA Ltd , Herzliya , Israel.
A P Kontosd UPMC Sports Medicine Concussion Program, Department of Orthopaedic Surgery , University of Pittsburgh , Pittsburgh , PA , USA.
Hewlett-Packard (Israel) · ILUniversity of Michigan–Ann Arbor · USUniversity of Pittsburgh · USUniversity of Arkansas at Fayetteville · US

Funding

Balance-Attention Interference Following ConcussionK01DC012332 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KONTOS, ANTHONY P · 2013 to 2017
$741k
NIDCD NIH HHS K01 DC012332
6 · The paper itself

Abstract

backgroundThe clinical diagnosis and management of patients with sport-related concussion is largely dependent on subjectively reported symptoms, clinical examinations, cognitive, balance, vestibular and oculomotor testing. Consequently, there is an unmet need for objective assessment tools that can identify the injury from a physiological perspective and add an important layer of information to the clinician's decision-making process.

objectiveThe goal of the study was to evaluate the clinical utility of the EEG-based tool named Brain Network Activation (BNA) as a longitudinal assessment method of brain function in the management of young athletes with concussion.

methodsAthletes with concussion (n = 86) and age-matched controls (n = 81) were evaluated at four time points with symptom questionnaires and BNA. BNA scores were calculated by comparing functional networks to a previously defined normative reference brain network model to the same cognitive task.

resultsSubjects above 16 years of age exhibited a significant decrease in BNA scores immediately following injury, as well as notable changes in functional network activity, relative to the controls. Three representative case studies of the tested population are discussed in detail, to demonstrate the clinical utility of BNA.

conclusionThe data support the utility of BNA to augment clinical examinations, symptoms and additional tests by providing an effective method for evaluating objective electrophysiological changes associated with sport-related concussions.

Indexed as

AdolescentAthletesAthletic InjuriesBrainBrain ConcussionCognitionElectroencephalographyFemaleHumansMaleNerve NetNeuropsychological TestsReaction TimeYoung AdultBrain Network Activation (BNA)Concussion managementelectroencephalogram (EEG)event related potential (ERP)functional brain imagingmild traumatic brain injury (mTBI)sports-related concussion (SRC)

Identifiers

PMID28055228
PMCPMC5351793
OpenAlexW2570882607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.