ArticleInvestigative ophthalmology & visual science2017
High-Resolution Imaging of Intraretinal Structures in Active and Resolved Central Serous Chorioretinopathy.
Article in Investigative ophthalmology & visual science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Association of Retinal Pigment Epithelium Pump Function Reversal with Choroidal Vascularity Index in Treatment-Naïve Central Serous Chorioretinopathy.Ophthalmology science · 2026Article
- Photoreceptors integrity as surrogate of retinal sensitivity in chronic central serous chorioretinopathy: a multimodal imaging study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Characterization of retinal pigment epithelium layer in healthy and diseased retinas with high-resolution adaptive optics transscleral flood illumination imaging.Acta ophthalmologica · 2026Article
- Longitudinal High-Resolution Imaging of Retinal Sequelae of a Choroidal Nevus.Diagnostics (Basel, Switzerland) · 2025Article
- Adaptive optics scanning laser ophthalmoscopy in a heterogenous cohort with Stargardt disease.Scientific reports · 2024Observational
- Quantitative optical coherence tomography angiography assessments in the fellow eyes of those with central serous chorioretinopathy.BMC ophthalmology · 2024Article
- Autofluorescent hyperreflective foci on infrared autofluorescence adaptive optics ophthalmoscopy in central serous chorioretinopathy.American journal of ophthalmology case reports · 2022Article
- Challenges Associated With Ellipsoid Zone Intensity Measurements Using Optical Coherence Tomography.Translational vision science & technology · 2021Article
- Dynamic changes and correlation analysis of outer retinal microstructure in macular area of central serous chorioretinopathy patients during restoration period.International ophthalmology · 2021Article
- Current Choroidal Imaging Findings in Central Serous Chorioretinopathy.Vision (Basel, Switzerland) · 2020Review
- Evaluation of choroidal hyperreflective dots in acute and chronic central serous chorioretinopathy.Indian journal of ophthalmology · 2019Article
- Commentary: Hyperreflective dots - An imaging biomarker of inflammation?Indian journal of ophthalmology · 2019Article
- Association between visual function and the integrity of residual ellipsoid zone in resolved central serous chorioretinopathy.Scientific reports · 2019Observational
- Outer nuclear layer thickness at the central fovea relation with symptom duration in central serous chorioretinopathy.International ophthalmology · 2019Article
- Adaptive optics scanning laser ophthalmoscopy in fundus imaging, a review and update.International journal of ophthalmology · 2017Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Purpose: We improved our understanding of central serous chorioretinopathy (CSC), we performed an analysis of noninvasive, high-resolution retinal imaging in patients with active and resolved CSC. Methods: Adaptive optics scanning light ophthalmoscopy (AOSLO) and spectral-domain optical coherence tomography (SD-OCT) were performed on five subjects with CSC. A custom AOSLO system was used to simultaneously collect confocal and split-detector images. Spectral domain-OCT volume scans were used to create en face views of various retinal layers, which then were compared to montaged AOSLO images after coregistration. Results: Three distinct types of intraretinal hyperreflective clusters were seen with AOSLO. These clusters had a well-demarcated, round, and granular appearance. Clusters in active CSC over areas of serous retinal detachment were termed type-1. They were found primarily in the outer nuclear layer (ONL) and were associated with large defects in the photoreceptor mosaic and ellipsoid zone. Clusters in areas where the retina had reattached were termed type-2. They also were located primarily in the ONL but showed stability in location over a period of at least 8 months. Smaller clusters in the inner retina along retinal capillaries were termed type-3. Conclusions: Retinal imaging in CSC using en face OCT and AOSLO allows precise localization of intraretinal structures and detection of features that cannot be seen with SD-OCT alone. These findings may provide greater insight into the pathophysiology of the active and resolved phases of the disease, and support the hypothesis that intraretinal hyperreflective foci on OCT in CSC are cellular in nature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.