Evidence map›Paper›PMID 28054961›Full record

ArticleMarine drugs2017

The In Vitro and In Vivo Anti-Inflammatory Effects of a Phthalimide PPAR-γ Agonist.

Mingzhi Su, Jiafu Cao, Jin Huang, Sen Liu, Dong Soon Im, Jin-Wook Yoo, Jee H Jung

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 50 citations in OpenAlex.

  1. Anti-Inflammatory Activity of Cyclic Imide Derivatives.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Phthalimides as anti-inflammatory agents.Future medicinal chemistry · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Scutellariae Radix and Citri Reticulatae Pericarpium Mixture Regulate PPAREvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  13. Anti-inflammatory activity of flavonolsCurrent research in food science · 2022
    Article
  14. Article
  15. A New N-Substituted 1International journal of molecular sciences · 2021
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mingzhi SuCollege of Pharmacy, Pusan National University, Busan 609-735, Korea. sumingzhi0310@gmail.com.
Jiafu CaoCollege of Pharmacy, Pusan National University, Busan 609-735, Korea. caojiafu1985@163.com.
Jin HuangCollege of Pharmacy, Pusan National University, Busan 609-735, Korea. jellyohuang@gmail.com.
Sen LiuCollege of Pharmacy, Pusan National University, Busan 609-735, Korea. ls691392008@sina.com.
Dong Soon ImCollege of Pharmacy, Pusan National University, Busan 609-735, Korea. imds@pusan.ac.kr.
Jin-Wook YooCollege of Pharmacy, Pusan National University, Busan 609-735, Korea. jinwook@pusa.ac.kr.
Jee H JungCollege of Pharmacy, Pusan National University, Busan 609-735, Korea. jhjung@pusan.ac.kr.
Pusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previously, the authors found that 4-hydroxy-2-(4-hydroxyphenethyl) isoindoline-1,3-dione (

Indexed as

AnimalsAnti-Inflammatory AgentsCell LineCytokinesHEK293 CellsHumansInflammationInflammation MediatorsMacrophagesMaleMiceNF-kappa BPhthalimidesPPAR gammaRatsRats, WistarAnti-Inflammatory AgentsCytokinesInflammation MediatorsNF-kappa BphthalimidePhthalimidesPPAR gammaanti-inflammatory effectcytokinesNF-κB pathwaypaw edemaphthalimide analoguePPAR-γ agonistRAW264.7 macrophage

Identifiers

PMID28054961
PMCPMC5295227
OpenAlexW2571314240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.