Evidence map›Paper›PMID 28054948›Full record

ArticleInternational journal of molecular sciences2017

rs657075 (CSF2) Is Associated with the Disease Phenotype (BAS-G) of Ankylosing Spondylitis.

Wei-Chiao Chen, James Cheng-Chung Wei, Hsing-Fang Lu, Henry Sung-Ching Wong, Peng Yeong Woon, Yu-Wen Hsu, Jin-Ding Huang, Wei-Chiao Chang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. rs2841277 (Oncotarget · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Wei-Chiao ChenInstitude of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan. doggyenjoying@yahoo.com.tw.
James Cheng-Chung WeiDivision of Allergy, Immunology and Rheumatology, Chung Shan Medical University Hospital, Taichung 40201, Taiwan. wei3228@gmail.com.
Hsing-Fang LuDepartment of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei 11014, Taiwan. shefunlu@gmail.com.
Henry Sung-Ching WongDepartment of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei 11014, Taiwan. miningyue@gmail.com.
Peng Yeong WoonDepartment of Molecular Biology and Human Genetics, Tzu Chi University, Hualien 97004, Taiwan. woon07@mail.tcu.edu.tw.
Yu-Wen HsuThe Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan. fish770426@hotmail.com.
Jin-Ding HuangInstitude of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan. jinding@mail.ncku.edu.tw.
Wei-Chiao ChangDepartment of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taipei 11014, Taiwan. wcc@tmu.edu.tw.
Academia Sinica · TWNational Cheng Kung University · TWTaipei Medical University · TWChung Shan Medical University · TWTzu Chi University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ankylosing spondylitis (AS) is a systemic autoimmune disease mainly affecting the lumbar spine and sacroiliac joints, and exhibits peripheral inflammatory arthropathy. More than 25 loci have been identified as associated with AS. Because both AS and rheumatoid arthritis (RA) are autoimmune diseases that may share some common genetic factors, we therefore examined if the newly identified RA genetic polymorphisms were associated with AS in a Taiwanese population. In this study, we enrolled 475 AS patients and 11,301 healthy subjects from a Taiwanese biobank as controls. Although none of single-nucleotide polymorphisms (SNPs) were associated with the susceptibility to AS, the AS disease index Bath AS Global (BAS-G) clinical phenotype was observed as significantly correlated to the AA genotype of rs657075 (

Indexed as

Polymorphism, Single NucleotideAdultArthritis, RheumatoidFemaleGenetic Predisposition to DiseaseGenotypeHLA-B27 AntigenHumansMaleMiddle AgedQuantitative Trait LociSeverity of Illness IndexSpondylitis, AnkylosingTaiwanHLA-B27 Antigenankylosing spondylitisBath AS Global (BAS-G)CSF2rs657075single nucleotide polymorphism

Identifiers

PMID28054948
PMCPMC5297717
OpenAlexW2563967283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.