Evidence map›Paper›PMID 28054582›Full record

ReviewGene therapy2017

Gene therapy approaches for prevention of retinal degeneration in Usher syndrome.

D S Williams, A Chadha, R Hazim, D Gibbs

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Gene therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. USH2A Gene Editing Using the CRISPR System.Molecular therapy. Nucleic acids · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

D S WilliamsStein Eye Institute, UCLA School of Medicine, Los Angeles, CA, USA.
A ChadhaStein Eye Institute, UCLA School of Medicine, Los Angeles, CA, USA.
R HazimStein Eye Institute, UCLA School of Medicine, Los Angeles, CA, USA.
D GibbsTranslational Neurosciences Institute, Department of Neurosciences, UCSD School of Medicine, La Jolla, CA, USA.
Neurosciences Institute · USUniversity of California, Los Angeles · US

Funding

Vision Research Core at UCLAP30EY000331 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Gregory Darin Field · 1985 to 2026
$16.8M
Vision Science Training ProgramT32EY007026 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Alapakkam P Sampath · 1985 to 2026
$5.7M
The Photoreceptor CiliumR01EY013408 · NEI · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI WILLIAMS, DAVID S · 2001 to 2017
$3.8M
Developing a noninvasive method to manipulate specific cell types within the mammalian brainR01MH111534 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI CHALASANI, SREEKANTH H. · 2016 to 2018
$3.1M
Functional characterization of MY07A in retinal tissueF32EY026318 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHADHA, ABHISHEK · 2016 to 2018
$174k
NEI NIH HHS F32 EY026318NEI NIH HHS P30 EY000331NEI NIH HHS R01 EY013408NEI NIH HHS T32 EY007026NIMH NIH HHS R01 MH111534
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic TherapyHumansRetinal DegenerationUsher Syndromes

Identifiers

PMID28054582
PMCPMC6055994
OpenAlexW2571206825

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.