ArticleInfection2017
A risk factor analysis for in-hospital mortality after surgery for infective endocarditis and a proposal of a new predictive scoring system.
Article in Infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Infective endocarditis: Do we have an effective risk score model? A systematic review.Frontiers in cardiovascular medicine · 2023Pooled it
- The impact of thrombocytopenia on mortality in infective endocarditis - aInternational journal of cardiology. Heart & vasculature · 2025Review
- Anemia and Transfusion in Infective Endocarditis.Reviews in cardiovascular medicine · 2025Review
- Infective endocarditis risk scores: a narrative review.Journal of thoracic disease · 2025Review
- Changing performance of surgical risk scores according to the endpoint of postoperative mortality in infective endocarditis patients.Frontiers in cardiovascular medicine · 2025Article
- Enhanced Risk Stratification in Infective Endocarditis Surgery: A Comprehensive External Validation of All Available Mortality Prediction Scores.Clinical epidemiology · 2025Article
- Surgery in patients with infective endocarditis and prognostic importance of patient frailty.Infection · 2024Article
- ASSESS-IE: a Novel Risk Score for Patients with Infective Endocarditis.Journal of cardiovascular translational research · 2024Article
- Perioperative risk stratification scores in infective endocarditis and its usefulness.Indian journal of thoracic and cardiovascular surgery · 2024Review
- Development and validation of a nomogram for predicting in-hospital mortality in ICU patients with infective endocarditis.BMC medical informatics and decision making · 2024Article
- Performance of the SHARPEN Score and the Charlson Comorbidity Index for In-Hospital and Post-Discharge Mortality Prediction in Infective Endocarditis.Arquivos brasileiros de cardiologia · 2024Article
- CHARMS and PROBAST at your fingertips: a template for data extraction and risk of bias assessment in systematic reviews of predictive models.BMC medical research methodology · 2023Article
- Fulminant infectious endocarditis caused byRadiology case reports · 2022Article
- Outcome of surgery for acute infective endocarditis: does preoperative stroke have an impact on mortality?Indian journal of thoracic and cardiovascular surgery · 2020Article
- Review
- Microbial biofilm correlates with an increased antibiotic tolerance and poor therapeutic outcome in infective endocarditis.BMC microbiology · 2019Article
- Should we include microorganisms in scores to predict outcome in candidates for cardiac surgery during the acute phase of endocarditis?Journal of thoracic disease · 2019Article
- Bugs at the operating theatre in infective endocarditis: one step forward, still a long way to go.Journal of thoracic disease · 2019Article
- A Case of Mitral Valve Endocarditis Complicated by Multiple Embolic Phenomena: Leaping from Adult Guidelines to Pediatric Critical Care Decisions.Journal of pediatric intensive care · 2019Article
- Contemporary risk models for infective endocarditis surgery: a narrative review.Therapeutic advances in cardiovascular diseaseReview
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeRisk stratification is of utmost importance for patients with infective endocarditis (IE) who need surgery. However, for these critically ill patients, aspecific scoring systems are used to predict the risk of death after surgery. The aim of this study was both to analyze the risk factors for in-hospital death, which complicates surgery for IE and to create a mortality risk score based on the results of this analysis.
methodsOutcomes of 138 consecutive patients (mean age 60.6 ± 8.5 years) who had undergone surgery for IE in an Italian cardiac surgery center between 1999 and 2015 were reviewed retrospectively and a risk factor analysis (multivariable logistic regression) for in-hospital death was performed. The discriminatory power of a new predictive scoring system was assessed with the receiver-operating characteristic (ROC) curve analysis.
resultsTwenty-eight (20.3%) patients died in hospital following surgery. Anemia [odds ratio (OR) 11.0, p = 0.035), New York Heart Association class IV (OR 2.61, p = 0.09), critical state (OR 4.97, p = 0.016), large intracardiac destruction (OR 6.45, p = 0.0014), and surgery of the thoracic aorta (OR 7.51, p = 0.041) were independent predictors of hospital death. A new scoring system was devised to predict in-hospital death after surgery for IE (area under ROC curve, 0.828, 95% confidence interval, 0.754-0.887). The score outperformed six of seven scoring systems, for early death after cardiac surgery, that were considered.
conclusionsA simple scoring system based on risk factors for in-hospital death was specifically created to predict mortality risk after surgery for IE. Prospective studies are needed for the score validation.
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