Evidence map›Paper›PMID 28054212›Full record

ArticleInternational ophthalmology2018

Assessing posterior ocular structures in β-thalassemia minor.

Hasan Basri Arifoglu, Bekir Kucuk, Necati Duru, Orhan Altunel, Ahmet Gulhan, Mustafa Ozen, Bilal Aygun, Mustafa Atas

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Unusual presentation of tractional retinal detachment in beta thalassemia minor.American journal of ophthalmology case reports · 2023
    Article
  3. Article
  4. Article
  5. Macular microvascular changes in children with transfusion-dependent beta-thalassemia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Observational
  6. Article
  7. Retinal nerve fiber layer thickness in children with β-thalassemia major.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hasan Basri ArifogluDepartment of Ophthalmology, Kayseri Education and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street No: 78, 38010, Kayseri, Turkey. habasa@yahoo.com.
Bekir KucukDepartment of Ophthalmology, Kayseri Education and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street No: 78, 38010, Kayseri, Turkey.
Necati DuruDepartment of Ophthalmology, Kayseri Education and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street No: 78, 38010, Kayseri, Turkey.
Orhan AltunelDepartment of Ophthalmology, Kayseri Education and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street No: 78, 38010, Kayseri, Turkey.
Ahmet GulhanDepartment of Ophthalmology, Kayseri Education and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street No: 78, 38010, Kayseri, Turkey.
Mustafa OzenDepartment of Haematology, Kayseri Education and Research Hospital, Kayseri, Turkey.
Bilal AygunDepartment of Haematology, Kayseri Education and Research Hospital, Kayseri, Turkey.
Mustafa AtasDepartment of Ophthalmology, Kayseri Education and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street No: 78, 38010, Kayseri, Turkey.
Kayseri Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to investigate the effect of β-thalassemia minor on choroidal, macular, and peripapillary retinal nerve fiber layer thickness.

methodsTo form the sample, we recruited 40 patients with β-thalassemia minor and 44 healthy participants. We used spectral-domain optical coherence tomography to take all measurements of ocular thickness, as well as measured intraocular pressure, axial length, and central corneal thickness. We later analyzed correlations of hemoglobin levels with ocular parameters.

resultsA statistically significant difference emerged between patients with β-thalassemia minor and the healthy controls in terms of mean values of subfoveal, nasal, and temporal choroidal thickness (p = 0.001, p = 0.016, and p = 0.010, respectively). Except for central macular thickness, differences in paracentral macular thicknesses between the groups were also significant (superior: p < 0.001, inferior: p = 0.007, temporal: p = 0.001, and nasal: p = 0.005). Also, no statistically significant differences were noted for retinal nerve fiber layer thickness between two groups.

conclusionMean values of subfoveal, nasal, temporal choroidal, and macular thickness for the four quadrants were significantly lower in patients with β-thalassemia minor than in healthy controls.

Indexed as

Adultbeta-ThalassemiaCase-Control StudiesChoroidCross-Sectional StudiesFemaleHumansMacula LuteaMaleMiddle AgedNerve FibersRetinaTomography, Optical CoherenceChoroidal thicknessEDI-OCTMacular thicknessRNFL thicknessβ-thalassemia minor

Identifiers

PMID28054212
OpenAlexW2568128651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.