ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018
Impact of pharmacological stress agent on patient motion during rubidium-82 myocardial perfusion PET/CT.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 29 citations in OpenAlex.
- Influence of patient motion on quantitative accuracy in cardiacJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- CardiacJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- The next step in improving (semi-)quantitative MPI PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- A preliminary evaluation of a high temporal resolution data-driven motion correction algorithm for rubidium-82 on a SiPM PET-CT system.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- The long fight against motion artifacts in cardiac PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Dynamic cardiac PET motion correction using 3D normalized gradient fields in patients and phantom simulations.Medical physics · 2021Article
- Assessment of motion correction in dynamic rubidium-82 cardiac PET with and without frame-by-frame adjustment of attenuation maps for calculation of myocardial blood flow.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Myocardial blood flow: Is motion correction necessary?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- EANM procedural guidelines for PET/CT quantitative myocardial perfusion imaging.European journal of nuclear medicine and molecular imaging · 2021Article
- Patient motion correction for dynamic cardiac PET: Current status and challenges.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Blood pool and tissue phase patient motion effects onJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- No need for frame-wise attenuation correction in dynamic Rubidium-82 PET for myocardial blood flow quantification.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Creeping towards broader clinical application of PET myocardial blood flow quantification.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- How to detect and correct myocardial creep in myocardial perfusion imaging using Rubidium-82 PET?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Impact of regadenoson-induced myocardial creep on dynamic Rubidium-82 PET myocardial blood flow quantification.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Gating Approaches in Cardiac PET Imaging.PET clinics · 2019Review
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2018. Part 1 of 2: Positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatient motion has been demonstrated to have a significant impact on the quality and accuracy of rubidium-82 myocardial perfusion PET/CT. This study aimed to investigate the effect on patient motion of two pharmacological stressing agents, adenosine and regadenoson. METHODS AND
resultsDynamic data were retrospectively analyzed in 90 patients undergoing adenosine (n = 30), incremental adenosine (n = 30), or regadenoson (n = 30) rubidium-82 myocardial perfusion PET/CT. Severity of motion was scored qualitatively using a four-point (0-3) scale and quantitatively using frame-to-frame pixel shifts. The type of motion, returning or non-returning, and the frame in which it occurred were also recorded. There were significant differences in both the qualitative and quantitative scores comparing regadenoson to adenosine (P = .025 and P < .001) and incremental adenosine (P = .014, P = .015), respectively. The difference in scores between adenosine and incremental adenosine was not significant. Where motion was present, significantly more adenosine patients were classed as non-returning (P = .018). The median frames for motion occurring were 12 for regadenoson and 14 for both adenosine cohorts.
conclusionsThe choice of stressing protocol impacts significantly on patient motion. Patients stressed with regadenoson have significantly lower motion scores than those stressed with adenosine, using local protocols. This motion is more likely to be associated with a drift of the heart away from a baseline position, coinciding with the termination of infusion.
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