ArticleArchives of toxicology2017
Inhalation of gas metal arc-stainless steel welding fume promotes lung tumorigenesis in A/J mice.
Article in Archives of toxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 26 citations in OpenAlex.
- Short- and long-term pathologic responses to quartz are induced by nearly free silanols formed during crystal fracturing.Particle and fibre toxicology · 2024Article
- Modelled lung deposition and retention of welding fume particles in occupational scenarios: a comparison to doses used in vitro.Archives of toxicology · 2022Article
- Lung toxicity profile of inhaled copper-nickel welding fume in A/J mice.Inhalation toxicology · 2022Article
- Toxicity of stainless and mild steel particles generated from gas-metal arc welding in primary human small airway epithelial cells.Scientific reports · 2021Article
- Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice.Methods in cell biology · 2021Article
- Tumorigenic response in lung tumor susceptible A/J mice after sub-chronic exposure to calcium chromate or iron (III) oxide.Toxicology letters · 2020Article
- Influence of welding fume metal composition on lung toxicity and tumor formation in experimental animal models.Journal of occupational and environmental hygiene · 2019Review
- Inhalation of iron-abundant gas metal arc welding-mild steel fume promotes lung tumors in mice.Toxicology · 2018Article
- Article
- Silica inhalation altered telomere length and gene expression of telomere regulatory proteins in lung tissue of rats.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
Epidemiologic studies suggest an increased risk of lung cancer with exposure to welding fumes, but controlled animal studies are needed to support this association. Oropharyngeal aspiration of collected "aged" gas metal arc-stainless steel (GMA-SS) welding fume has been shown by our laboratory to promote lung tumor formation in vivo using a two-stage initiation-promotion model. Our objective in this study was to determine whether inhalation of freshly generated GMA-SS welding fume also acts as a lung tumor promoter in lung tumor-susceptible mice. Male A/J mice received intraperitoneal (IP) injections of corn oil or the chemical initiator 3-methylcholanthrene (MCA; 10 µg/g) and 1 week later were exposed by whole-body inhalation to air or GMA-SS welding aerosols for 4 h/d × 4 d/w × 9 w at a target concentration of 40 mg/m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.