Evidence map›Paper›PMID 28053993›Full record

ArticleJournal of immunology research2016

High Triglycerides Are Associated with Low Thrombocyte Counts and High VEGF in Nephropathia Epidemica.

Ekaterina V Martynova, Aygul H Valiullina, Oleg A Gusev, Yuriy N Davidyuk, Ekaterina E Garanina, Venera G Shakirova, Ilsiyar Khaertynova, Vladimir A Anokhin, Albert A Rizvanov, Svetlana F Khaiboullina

Open access · goldAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. ΔViruses · 2019
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Ekaterina V MartynovaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Tatarstan, Russia.ORCID 0000-0003-1537-3099
Aygul H ValiullinaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Tatarstan, Russia.
Oleg A GusevInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Tatarstan, Russia; RIKEN, Yokohama, Japan.
Yuriy N DavidyukInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Tatarstan, Russia.
Ekaterina E GaraninaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Tatarstan, Russia.
Venera G ShakirovaKazan State Medical Academy, Kazan, Tatarstan, Russia.
Ilsiyar KhaertynovaKazan State Medical Academy, Kazan, Tatarstan, Russia.
Vladimir A AnokhinKazan State Medical Academy, Kazan, Tatarstan, Russia.ORCID 0000-0003-1050-9081
Albert A RizvanovInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Tatarstan, Russia.ORCID 0000-0002-9427-5739
Svetlana F KhaiboullinaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Tatarstan, Russia; University of Nevada, Reno, NV, USA.ORCID 0000-0002-5064-570X
Kazan Federal University · RUKazan State Medical Academy · RUUniversity of Nevada, Reno · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nephropathia epidemica (NE) is a mild form of hemorrhagic fever with renal syndrome. Several reports have demonstrated a severe alteration in lipoprotein metabolism. However, little is known about changes in circulating lipids in NE. The objectives of this study were to evaluate changes in serum total cholesterol, high density cholesterol (HDCL), and triglycerides. In addition to evaluation of serum cytokine activation associations, changes in lipid profile and cytokine activation were determined for gender, thrombocyte counts, and VEGF. Elevated levels of triglycerides and decreased HDCL were observed in NE, while total cholesterol did not differ from controls. High triglycerides were associated with both the lowest thrombocyte counts and high serum VEGF, as well as a high severity score. Additionally, there were higher levels of triglycerides in male than female NE patients. Low triglycerides were associated with upregulation of IFN-

Indexed as

Platelet CountAdultCholesterolCholesterol, HDLCytokinesFemaleHemorrhagic Fever with Renal SyndromeHumansInterferon-gammaInterleukin-12MalePeptide FragmentsSeverity of Illness IndexSex CharacteristicsTh1 CellsTriglyceridesCholesterolCholesterol, HDLCytokinesInterferon-gammainterferon gamma (1-39)Interleukin-12Peptide FragmentsTriglyceridesVascular Endothelial Growth Factor A

Identifiers

PMID28053993
PMCPMC5178363
OpenAlexW2560604489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.