Evidence map›Paper›PMID 28053947›Full record

ArticleThe world journal of men's health2016

Anti-Inflammatory and Antimicrobial Effects of a Novel Herbal Formulation (WSY-1075) in a Chronic Bacterial Prostatitis Rat Model.

Jung Woo Park, Hyun Cheol Jeong, Hyong Woo Moon, Shin Jay Cho, Jong Hyup Yang, Woo Hyun Kim, Woong Jin Bae, Jin Bong Choi, Hyuk Jin Cho, U-Syn Ha and 3 more

Open access · diamondAbstract read
In one paragraph

Article in The world journal of men's health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Jung Woo ParkDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Hyun Cheol JeongDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Hyong Woo MoonDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Shin Jay ChoDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Jong Hyup YangDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Woo Hyun KimDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Woong Jin BaeDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Catholic Integrative Medicine Research Institute, The Catholic University of Korea, Seoul, Korea.
Jin Bong ChoiDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Hyuk Jin ChoDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
U-Syn HaDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Sung Hoo HongDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Ji Youl LeeDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Sae Woong KimDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.; Catholic Integrative Medicine Research Institute, The Catholic University of Korea, Seoul, Korea.
Catholic University of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to investigate the anti-inflammatory and anti-oxidative effects of a multi-herbal formula known as WSY-1075 in the treatment of chronic bacterial prostatitis in a rat model. MATERIALS AND

methodsExperimental chronic bacterial prostatitis was induced in 32 Wistar rats by instillation of a bacterial suspension (

resultsThe WSY-1075, ciprofloxacin, and WSY-1075+ciprofloxacin groups showed fewer CFUs in prostate tissue cultures than the control group. The WSY-1075, ciprofloxacin and WSY-1075+ciprofloxacin groups showed statistically significantly lower levels of the pro-inflammatory cytokines TNF-α, IL-6, and IL-8 than the control group. SOD levels in the WSY-1075, ciprofloxacin and WSY-1075+ciprofloxacin groups were significantly higher than in the control group.

conclusionsThis study found that WSY-1075 had anti-microbial effects, anti-inflammatory effects, and anti-oxidative effects in a chronic bacterial prostatitis rat model. We expect the WSY-1075 may be useful for the clinical treatment of chronic bacterial prostatitis.

Indexed as

HerbalsProstatitisRats

Identifiers

PMID28053947
PMCPMC5209558
OpenAlexW2565264152

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.