Trial reportNeural plasticity2016
Pain Induced during Both the Acquisition and Retention Phases of Locomotor Adaptation Does Not Interfere with Improvements in Motor Performance.
Trial report in Neural plasticity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Motor Learning in Response to Different Experimental Pain Models Among Healthy Individuals: A Systematic Review.Frontiers in human neuroscience · 2022Pooled it
- Exploring pain interference with motor skill learning in humans: A systematic review.PloS one · 2022Pooled it
- Acute pain impairs retention of locomotor learning, regardless of the context of retention testing.Journal of neurophysiology · 2025Trial
- Acute pain impairs retention of locomotor learning.Journal of neurophysiology · 2024Trial
- The effect of eccentric exercise-induced delayed onset neck muscle soreness on force steadiness and the spatial distribution of neck extensor muscle activity.Scientific reports · 2026Article
- Effect of Phasic Experimental Pain Applied during Motor Preparation or Execution on Motor Performance and Adaptation in a Reaching Task: A Randomized Trial.Brain sciences · 2024Article
- An Innovative EEG-Based Pain Identification and Quantification: A Pilot Study.Sensors (Basel, Switzerland) · 2024Article
- Towards the Objective Identification of the Presence of Pain Based on Electroencephalography Signals' Analysis: A Proof-of-Concept.Sensors (Basel, Switzerland) · 2022Article
- Does musculoskeletal pain interfere with motor learning in a gait adaptation task? A proof-of-concept study.BMC musculoskeletal disorders · 2022Article
- Learning Gait Modifications for Musculoskeletal Rehabilitation: Applying Motor Learning Principles to Improve Research and Clinical Implementation.Physical therapy · 2021Article
- Ankle proprioception during gait in individuals with incomplete spinal cord injury.Physiological reports · 2019Article
- Corticomotor excitability reduction induced by experimental pain remains unaffected by performing a working memory task as compared to staying at rest.Experimental brain research · 2019Article
- Motor adaptations to trunk perturbation: effects of experimental back pain and spinal tissue creep.Journal of neurophysiology · 2018Article
- Effect of movement-related pain on behaviour and corticospinal excitability changes associated with arm movement preparation.The Journal of physiology · 2018Article
- Effect of Cutaneous Heat Pain on Corticospinal Excitability of the Tibialis Anterior at Rest and during Submaximal Contraction.Neural plasticity · 2018Article
- Effect of Experimental Hand Pain on Training-Induced Changes in Motor Performance and Corticospinal Excitability.Brain sciences · 2017Article
- Pain-induced Impact on Movement: Motor Coordination Variability and Accuracy-based Skill.Basic and clinical neuroscienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Cutaneous pain experienced during locomotor training was previously reported to interfere with retention assessed in pain-free conditions. To determine whether this interference reflects consolidation deficits or a difficulty to transfer motor skills acquired in the presence of pain to a pain-free context, this study evaluated the effect of pain induced during both the acquisition and retention phases of locomotor learning. Healthy participants performed a locomotor adaptation task (robotized orthosis perturbing ankle movements during swing) on two consecutive days. Capsaicin cream was applied around participants' ankle on both days for the Pain group, while the Control group was always pain-free. Changes in movement errors caused by the perturbation were measured to assess global motor performance; temporal distribution of errors and electromyographic activity were used to characterize motor strategies. Pain did not interfere with global performance during the acquisition or the retention phases but was associated with a shift in movement error center of gravity to later in the swing phase, suggesting a reduction in anticipatory strategy. Therefore, previously reported retention deficits could be explained by contextual changes between acquisition and retention tests. This difficulty in transferring skills from one context to another could be due to pain-related changes in motor strategy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.