ArticleSpinal cord series and cases2015
Cervical intramedullary immature teratoma with metastatic recurrence in an adult.
Article in Spinal cord series and cases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- Intramedullary cervical spinal cord teratoma.Medicine · 2020Pooled it
- Intradural Extramedullary Spinal Cord Malignancy Treated With Percutaneous Image-Guided Cryoablation.Cureus · 2025Article
- Intradural-Intramedullary Spinal Teratoma with Syrinx Formation: A Case Report.Clinical medicine insights. Case reports · 2025Article
- Article
- Acute regrowth and dissemination of a mature spinal cord teratoma after partial resection.BMJ case reports · 2018Article
- Osteosarcoma Arising From a Cervical Teratoma in a 4-year Old Child: A Report of a Rare Case and Literature Review.Journal of the West African College of SurgeonsArticle
Corrections and comments
- Erratum issuedErratum for2016
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designCase report.
objectivesWe present for the first time an adult patient with cervical intramedullary immature teratoma with metastatic recurrence.
settingPeking university Shenzhen Hospital, Shenzhen, China.
methodsA 30-year-old woman presented with rapidly progressive quadriplegia. Magnetic resonance imaging (MRI) revealed an intramedullary tumor occupying C1-C2 of the upper spinal cord. An urgent operation, consisting of decompression by laminectomy and tumor gross resection, was performed under a preoperative diagnosis of spinal glioma. The histological diagnosis was immature teratoma. The patient received local radiotherapy after gross total resection. The serum alpha fetoprotein (AFP) and human chorionic gonadotropin (HCG) levels were normal postoperatively, until these were evaluated on the 10th month with neurological deterioration. Metastatic recurrences were demonstrated on MRI with lesions located at the levels of C5-C6 and T11-12. Removal of the second tumors was performed and the pathological examination identified a malignant germ cell tumor (yolk sac tumor). The patient was then referred to chemotherapy and radiotherapy.
resultsNo tumor regrowth was encountered and the patient remained stable for 6 months after adjuvant therapy.
conclusionImmature teratoma should be included in the differential diagnosis of holocord tumors in the adult with rapidly progressing symptoms and if found should be radically excised if possible. Adjuvant therapy should be the salvage therapy for this recurrent tumor.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.