ArticleJournal of breast cancer2016
Predictive Factors for Upgrading Patients with Benign Breast Papillary Lesions Using a Core Needle Biopsy.
Article in Journal of breast cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Upgrade Rate and Predictive Factors for Breast Benign Intraductal Papilloma Diagnosed at Biopsy: A Meta-Analysis.Annals of surgical oncology · 2021Pooled it
- Investigation of Factors Affecting Histopathological Upgrade in Breast Papillary Lesions: A Single-Center Study.Breast care (Basel, Switzerland) · 2026Article
- High-Risk Benign Breast Lesions: An Ontario Health (Cancer Care Ontario) Recommendations Report.Current oncology (Toronto, Ont.) · 2026Review
- Papillary lesions of breast on core-needle biopsy: Factors associated with malignant upgrade on surgical excision.Journal of clinical imaging science · 2026Article
- Predicting radiological regression in benign breast hyperplasia: the prolactin-to-estradiol ratio as a prognostic biomarker.Frontiers in medicine · 2026Article
- A Rare Case of Mucinous Carcinoma Arising in Association with an Intraductal Papilloma.Surgical case reports · 2026Article
- High-Risk Breast Lesions on Core Biopsy: Rates of Upgrade and Management Recommendations.Surgical pathology clinics · 2025Review
- Clinicopathological and Imaging Features of Breast Papillary Lesions and Their Association with Pathologic Nipple Discharge.Diagnostics (Basel, Switzerland) · 2023Article
- Intraductal Papilloma of the Breast: Prevalence of Malignancy and Natural History Under Active Surveillance.Annals of surgical oncology · 2021Article
- Results of Excision of Unknown Papillary Neoplasms Detected on Core Biopsy.European journal of breast health · 2021Article
- High-risk lesions of the breast: concurrent diagnostic tools and management recommendations.Insights into imaging · 2021Review
- Papillary neoplasms of the breast including upgrade rates and management of intraductal papilloma without atypia diagnosed at core needle biopsy.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021Review
- Performance of a clinical and imaging-based multivariate model as decision support tool to help save unnecessary surgeries for high-risk breast lesions.Breast cancer research and treatment · 2021Article
- Factors associated with disease upgrading in patients with papillary breast lesion in core-needle biopsy.Gland surgery · 2020Article
- Unusual recurrent metastasizing benign breast papilloma: a case report.Journal of medical case reports · 2020Article
- Benign breast papillary lesions diagnosed on core biopsy: upgrade rate and risk factors associated with malignancy on surgical excision.Virchows Archiv : an international journal of pathology · 2019Article
- Papillary breast lesions diagnosed by percutaneous needle biopsy: management approach.Ecancermedicalscience · 2019Article
- Are we overtreating intraductal papillomas?The Journal of surgical research · 2018Article
- How Do We Approach Benign Proliferative Lesions?Current oncology reports · 2018Review
- Benign Intraductal Papilloma without Atypia on Core Needle Biopsy Has a Low Rate of Upgrading to Malignancy after Excision.Journal of breast cancer · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIntraductal papilloma (IDP) is a benign breast disease with malignant potential, for which complete surgical excision is usually recommended. The aim of the present study was to investigate predictive factors for upgrading patients with a benign papillary lesion (BPL).
methodsThis study was an observational study using a prospectively collected cohort. In total, 13,049 patients who underwent a core needle biopsy (CNB) for a breast lesion between January 2009 and May 2015 were enrolled. We reviewed all patients with pathologically confirmed BPL from a CNB.
resultsSurgical treatment was performed for 363 out of a total of 592 lesions. According to the pathological differences, the lowest upgrade rate was shown in IDP without atypia (without atypia, 6.0%; with atypia, 26.8%; papillary neoplasm, 31.5%;
conclusionThe indications for surgical treatment can be defined as age >54 years and mass size >1 cm, even in IDP without atypia in the CNB results; this also includes cases of IDP with atypia or papillary neoplasm. Therefore, we suggest that close observation without surgery is sufficient for younger women with a small IDP without atypia.
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