Evidence map›Paper›PMID 28053595›Full record

ArticleArchaea (Vancouver, B.C.)2016

Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea.

Laurence Prunetti, Michael Graf, Ian K Blaby, Lauri Peil, Andrea M Makkay, Agata L Starosta, R Thane Papke, Tairo Oshima, Daniel N Wilson, Valérie de Crécy-Lagard

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archaea (Vancouver, B.C.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Translation elongation factor P (EF-P).FEMS microbiology reviews · 2020
    Review
  3. Article
  4. Article
  5. Structural Study of Agmatine Iminohydrolase FromFrontiers in plant science · 2019
    Article
  6. Polyamine function in archaea and bacteria.The Journal of biological chemistry · 2018
    Review
  7. Article
  8. Modification of translation factor aIF5A from Sulfolobus solfataricus.Extremophiles : life under extreme conditions · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Laurence PrunettiDepartment of Microbiology and Cell Science, Institute for Food and Agricultural Sciences and Genetic Institute, University of Florida, P.O. Box 110700, Gainesville, FL 32611-0700, USA.ORCID 0000-0002-4588-1070
Michael GrafGene Center and Department for Biochemistry, University of Munich, 81377 Munich, Germany; Center for Integrated Protein Science Munich, University of Munich, 81377 Munich, Germany.
Ian K BlabyDepartment of Microbiology and Cell Science, Institute for Food and Agricultural Sciences and Genetic Institute, University of Florida, P.O. Box 110700, Gainesville, FL 32611-0700, USA.
Lauri PeilFaculty of Science and Technology, Institute of Technology, University of Tartu, Tartu, Estonia.ORCID 0000-0001-6906-7113
Andrea M MakkayDepartment of Molecular and Cell Biology, University of Connecticut, 91 N. Eagleville Rd, Storrs, CT 06269, USA.
Agata L StarostaGene Center and Department for Biochemistry, University of Munich, 81377 Munich, Germany; Center for Integrated Protein Science Munich, University of Munich, 81377 Munich, Germany.
R Thane PapkeDepartment of Molecular and Cell Biology, University of Connecticut, 91 N. Eagleville Rd, Storrs, CT 06269, USA.
Tairo OshimaInstitute of Environmental Microbiology, Kyowa Kako Co. Ltd., Tadao 2-15-5, Machida 194-0035, Japan.
Daniel N WilsonGene Center and Department for Biochemistry, University of Munich, 81377 Munich, Germany; Center for Integrated Protein Science Munich, University of Munich, 81377 Munich, Germany.
Valérie de Crécy-LagardDepartment of Microbiology and Cell Science, Institute for Food and Agricultural Sciences and Genetic Institute, University of Florida, P.O. Box 110700, Gainesville, FL 32611-0700, USA.ORCID 0000-0002-9955-3785
Center for Integrated Protein Science Munich · DEUniversity of Florida · USUniversity of Connecticut · USKyowa-kako (Japan) · JPUniversity of Tartu · EE

Funding

Synthesis and function of Queuosine in BacteriaR01GM070641 · NIGMS · UNIVERSITY OF FLORIDA · PI DE CRECY-LAGARD, VALERIE A · 2006 to 2023
$5.3M
NIGMS NIH HHS R01 GM070641
6 · The paper itself

Abstract

Translation initiation factor 5A (IF5A) is essential and highly conserved in Eukarya (eIF5A) and Archaea (aIF5A). The activity of IF5A requires hypusine, a posttranslational modification synthesized in Eukarya from the polyamine precursor spermidine. Intracellular polyamine analyses revealed that agmatine and cadaverine were the main polyamines produced in

Indexed as

Protein Processing, Post-TranslationalArchaeal ProteinsChromatography, LiquidHaloferax volcaniiLysinePeptide Initiation FactorsTandem Mass SpectrometryArchaeal ProteinshypusineLysinePeptide Initiation Factors

Identifiers

PMID28053595
PMCPMC5178350
OpenAlexW2560256034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.