ReviewJournal of neurophysiology2017
Distinct neural circuits for control of movement vs. holding still.
Review in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed.
- Distinct Roles of Directional and Positional Experience in De Novo Visuomotor Learning.eNeuro · 2026Article
- Mechanisms of Visuomotor Interception.Brain sciences · 2026Review
- A Spinal Origin for the Obligate Flexor Synergy in the Nonhuman Primate: Implications for Control of Reaching.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Article
- Neurophysiology of Gaze Direction as Poly-Equilibrium.NeuroSci · 2025Review
- Online Movements Reflect Ongoing Deliberation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- A spinal origin for the obligate flexor synergy in the non-human primate: Implications for control of reaching.bioRxiv : the preprint server for biology · 2025Article
- Article
- Article
- Brain network pathophysiology in dystonia.Dystonia (Lausanne, Switzerland) · 2025Article
- A video-oculography study of fixation instability in myasthenia gravis.Frontiers in neurology · 2025Article
- Realistic mossy fiber input patterns to unipolar brush cells evoke a continuum of temporal responses comprised of components mediated by different glutamate receptors.bioRxiv : the preprint server for biology · 2024Article
- Article
- Gastrocnemius Neuromuscular Activation During Standing Explosive Acceleration.Life (Basel, Switzerland) · 2024Article
- Motor cortical inactivation impairs corrective submovements in mice performing a hold-still center-out reach task.Journal of neurophysiology · 2024Article
- Incidence and predictors of postural abnormalities in Parkinson's disease: a PPMI cohort study.Journal of neurology · 2024Article
- The olivary input to the cerebellum dissociates sensory events from movement plans.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Central mechanisms of muscle tone regulation: implications for pain and performance.Frontiers in neuroscience · 2024Article
- Effects of the Specific Eye Fixation Training on Fine Visuomotor Coordination in Children with Attention Deficit Hyperactivity Disorder.Children (Basel, Switzerland) · 2023Article
- Article
Corrections and comments
- Erratum issuedCORRIGENDUM.2019
Authors and funding
1 author.
Funding
Abstract
In generating a point-to-point movement, the brain does more than produce the transient commands needed to move the body part; it also produces the sustained commands that are needed to hold the body part at its destination. In the oculomotor system, these functions are mapped onto two distinct circuits: a premotor circuit that specializes in generating the transient activity that displaces the eyes and a "neural integrator" that transforms that transient input into sustained activity that holds the eyes. Different parts of the cerebellum adaptively control the motor commands during these two phases: the oculomotor vermis participates in fine tuning the transient neural signals that move the eyes, monitoring the activity of the premotor circuit via efference copy, whereas the flocculus participates in controlling the sustained neural signals that hold the eyes, monitoring the activity of the neural integrator. Here, I review the oculomotor literature and then ask whether this separation of control between moving and holding is a design principle that may be shared with other modalities of movement. To answer this question, I consider neurophysiological and psychophysical data in various species during control of head movements, arm movements, and locomotion, focusing on the brain stem, motor cortex, and hippocampus, respectively. The review of the data raises the possibility that across modalities of motor control, circuits that are responsible for producing commands that change the sensory state of a body part are distinct from those that produce commands that maintain that sensory state.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.