SynthesisMedical mycology2017
Bone and joint infections caused by mucormycetes: A challenging osteoarticular mycosis of the twenty-first century.
Synthesis in Medical mycology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Brazilian task force for the management of mucormycosis.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesGuideline
- Upper limb mucormycosis in a patient with acute lymphoblastic leukemia: a case report.International journal of surgery case reports · 2026Article
- Mucormycotic osteomyelitis following anterior cruciate ligament reconstruction: A case report and literature review.Medical mycology case reports · 2026Article
- Recognizing the Early Risk-Based Clinical Manifestations of Mucormycosis: Cornerstones for Improved Survival and Therapeutic Outcomes.Journal of fungi (Basel, Switzerland) · 2025Article
- Commemorating the Landmark Advances in Our Understanding of Mucormycosis by Dimitrios P. Kontoyiannis.Journal of fungi (Basel, Switzerland) · 2025Article
- Delay in the Diagnosis of Osteoarticular Mucormycosis in Diabetic Ketoacidosis: A Learning Opportunity.Cureus · 2025Article
- Diagnosis and management of invasive fungal infections due to non-Aspergillus moulds.The Journal of antimicrobial chemotherapy · 2025Review
- A case series of 99mTc-MDP bone scintigraphy (planar and SPECT CT) in mucormycosis in the era of COVID 19.Frontiers in radiology · 2025Article
- Epidemiology, pathogenesis, clinical characteristics, and treatment of mucormycosis: a review.Annals of medicine · 2024Review
- Osteoarticular mucormycosis of the distal femur in a post COVID-19 patient.Medical mycology case reports · 2024Article
- Mucor mycosis of tibia: A case report of An unsolved entity.Journal of clinical orthopaedics and trauma · 2024Article
- Fracture-Related Infection of the Lower Limb Caused by Mucor velutinosus: Amputation or Salvation?Cureus · 2024Article
- Deep Sternal Wound Infection Caused byOpen forum infectious diseases · 2024Article
- The Impact of Dimitrios P. Kontoyiannis on Mucormycosis Research.Journal of fungi (Basel, Switzerland) · 2024Article
- Article
- Pulmonary Mucormycosis with Rib Involvement in an Immunocompromised Patient.American journal of respiratory and critical care medicine · 2023Article
- Exploring the Antimicrobial Activity of Sodium Titanate Nanotube Biomaterials in Combating Bone Infections: An In Vitro and In Vivo Study.Antibiotics (Basel, Switzerland) · 2023Article
- Mucor osteomyelitis after traumatic forearm amputation in a 38-year-old patient.Case reports in plastic surgery & hand surgery · 2023Article
- Osteoarticular Mycoses.Clinical microbiology reviews · 2022Review
- Spondylodiscitis associated with skin lesions caused byLe infezioni in medicina · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 8 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteomyelitis and arthritis caused by mucormycetes are rare diseases that rank among the most challenging complications in orthopedic and trauma surgery. The aim of this work is to review the epidemiological, clinical, diagnostic, and therapeutic aspects of the osteoarticular mucormycosis with particular emphasis on high-risk patients. A systematic review of osteoarticular mucormycosis was performed using PUBMED and EMBASE databases from 1978 to 2014. Among 34 patients with median age 41 (0.5-73 years), 24 (71%) were males. While 12 (35%) were immunocompromised patients, 14 (41%) had prior surgery, and seven (21%) suffered trauma. Other underlying conditions included diabetes mellitus, hematological malignancies, transplantation, and corticosteroid therapy. The median diagnostic delay from onset of symptoms and signs was 60 (10-180) days. The principal mechanism of the infection was direct inoculation (n = 19; 56%), and in immunocompromised patients was usually hematogenous disseminated. The long bones were infected by trauma or surgery, while a wide variety of bones were involved by hematogenous dissemination. Combined surgery and amphotericin B treatment were implemented in 28 (82%) and eight (23%) had an unfavorable outcome. Osteoarticular mucormycosis occurs most frequently after trauma or surgical procedures. These infections are progressively destructive and more virulent in individuals with impaired immune systems. Early diagnosis, timely administration of amphotericin B, control of underlying conditions, and surgical debridement of infected tissue are critical for successful management of osteoarticular mucormycosis.
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