Evidence map›Paper›PMID 28053023›Full record

Trial reportClinical cancer research : an official journal of the American Association for Cancer Research2017

Ricolinostat, the First Selective Histone Deacetylase 6 Inhibitor, in Combination with Bortezomib and Dexamethasone for Relapsed or Refractory Multiple Myeloma.

Dan T Vogl, Noopur Raje, Sundar Jagannath, Paul Richardson, Parameswaran Hari, Robert Orlowski, Jeffrey G Supko, David Tamang, Min Yang, Simon S Jones and 3 more

Registry-linked trialOpen access · greenAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02670746 (Non-interventional Observational Post-authorization Study to Assess Clinical and Patient Reported Outcomes With Nab-paclitaxel in Combination With Gemcitabine in Routine Clinical Practice Treating Pancreatic Cancer), which is not on this map. Cited by 147 papers.

0numbers the graph read from it
0cells of the map it votes in
147citing papers in PubMed
21.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02670746 terminatednot on this map

Non-interventional Observational Post-authorization Study to Assess Clinical and Patient Reported Outcomes With Nab-paclitaxel in Combination With Gemcitabine in Routine Clinical Practice Treating Pancreatic Cancer (TRUST)

TypeobservationalSponsorCelgeneRan2015 to 2017Enrolled44ConditionsPancreatic Neoplasms
3 · Its place in the literature

Who cites it

147 citing papers in PubMed, 249 citations in OpenAlex.

  1. Trial
  2. Research progress on lysine acetylation (Review).International journal of molecular medicine · 2026
    Review
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87 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Dan T VoglAbramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania. dan.vogl@uphs.upenn.edu.
Noopur RajeMassachusetts General Hospital, Boston, Massachusetts.
Sundar JagannathMount Sinai Medical Center, New York, New York.
Paul RichardsonDana Farber Cancer Institute, Boston, Massachusetts.
Parameswaran HariMedical College of Wisconsin, Milwaukee, Wisconsin.
Robert OrlowskiMD Anderson Cancer Center, Houston, Texas.
Jeffrey G SupkoMassachusetts General Hospital, Boston, Massachusetts.
David TamangAcetylon Pharmaceuticals Inc., Boston, Massachusetts.
Min YangAcetylon Pharmaceuticals Inc., Boston, Massachusetts.
Simon S JonesAcetylon Pharmaceuticals Inc., Boston, Massachusetts.
Catherine WheelerAcetylon Pharmaceuticals Inc., Boston, Massachusetts.
Robert J MarkelewiczAcetylon Pharmaceuticals Inc., Boston, Massachusetts.
Sagar LonialEmory University, Atlanta, Georgia.
Harvard University · USMedical College of Wisconsin · USThe University of Texas MD Anderson Cancer Center · US

Funding

Improving current therapies for myelomaK23CA130074 · NCI · UNIVERSITY OF PENNSYLVANIA · PI VOGL, DAN TOBY · 2009 to 2013
$862k
NCI NIH HHS K23 CA130074
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAntineoplastic Combined Chemotherapy ProtocolsBortezomibDexamethasoneDrug Resistance, NeoplasmFemaleHistone Deacetylase 6Histone Deacetylase InhibitorsHumansHydroxamic AcidsMaleMaximum Tolerated DoseMiddle AgedMultiple MyelomaNeoplasm Recurrence, LocalBortezomibDexamethasoneHDAC6 protein, humanHistone Deacetylase 6Histone Deacetylase InhibitorsHydroxamic AcidsPyrimidinesricolinostat

Identifiers

PMID28053023
PMCPMC5496796
OpenAlexW2569372699

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.