ArticleInfection and immunity2017
RAGE-Mediated Suppression of Interleukin-10 Results in Enhanced Mortality in a Murine Model of Acinetobacter baumannii Sepsis.
Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes.Nature communications · 2019Pooled it
- The impact of RAGE inhibition in animal models of bacterial sepsis: a systematic review and meta-analysis.The Journal of international medical research · 2018Pooled it
- Integrated Transcriptomic Analysis of S100A8/A9 as a Key Biomarker and Therapeutic Target in Sepsis Pathogenesis and AI Drug Repurposing.International journal of molecular sciences · 2025Article
- Insights intoFrontiers in immunology · 2022Review
- Polymyxin B, Cefoperazone Sodium-Sulbactam Sodium, and Tigecycline against Multidrug-ResistantEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Chronic oral exposure to glycated whey proteins increases survival of aged male NOD mice with autoimmune prostatitis by regulating the gut microbiome and anti-inflammatory responses.Food & function · 2020Article
- IL-10 Protects Mice From the Lung Infection ofFrontiers in immunology · 2020Article
- Host Innate Immune Responses toFrontiers in cellular and infection microbiology · 2020Review
- Suppressors of Cytokine Signaling (SOCS)1 and SOCS3 Proteins Are Mediators of Interleukin-10 Modulation of Inflammatory Responses Induced byMediators of inflammation · 2020Article
- Confronting Tigecycline-ResistantFrontiers in microbiology · 2020Article
- Potential Mechanisms of Mucin-Enhanced Acinetobacter baumannii Virulence in the Mouse Model of Intraperitoneal Infection.Infection and immunity · 2019Article
- Baicalin modulates apoptosis via RAGE, MAPK, and AP-1 in vascular endothelial cells duringInnate immunity · 2019Article
- Anti-outer Membrane Vesicle Antibodies Increase Antibiotic Sensitivity of Pan-Drug-ResistantFrontiers in microbiology · 2019Article
- Endogenous Uteroglobin as Intrinsic Anti-inflammatory Signal Modulates Monocyte and Macrophage Subsets Distribution Upon Sepsis Induced Lung Injury.Frontiers in immunology · 2019Article
- Coalescence of RAGE in Lipid Rafts in Response to Cytolethal Distending Toxin-Induced Inflammation.Frontiers in immunology · 2019Article
- Assessing Acinetobacter baumannii Virulence and Persistence in a Murine Model of Lung Infection.Methods in molecular biology (Clifton, N.J.) · 2019Article
- Sulfasalazine treatment can cause a positive effect on LPS-induced endotoxic rats.Experimental animals · 2018Article
- Expanding the Current Knowledge About the Role of Interleukin-10 to Major Concerning Bacteria.Frontiers in microbiology · 2018Review
- Article
- Myosin light chain kinase knockout improves gut barrier function and confers a survival advantage in polymicrobial sepsis.Molecular medicine (Cambridge, Mass.) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The receptor for advanced glycation end products (RAGE) is a pattern recognition receptor capable of recognizing multiple pathogen-associated and danger-associated molecular patterns that contributes to the initiation and potentiation of inflammation in many disease processes. During infection, RAGE functions to either exacerbate disease severity or enhance pathogen clearance depending on the pathogen studied.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.