Evidence map›Paper›PMID 28052951›Full record

ArticleBMJ case reports2017

Is haloperidol the wonder drug for cannabinoid hyperemesis syndrome?

Faisal Inayat, Hafeez Ul Hassan Virk, Waqas Ullah, Qulsoom Hussain

Registry-linked trialOpen access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06395428 (Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06395428 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department

TypeinterventionalSponsorWestern Michigan University School of MedicineRan2024 to 2027Enrolled75ConditionsBack Pain, Chronic PainArmsHaloperidol, Ketorolac Tromethamine
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. A Systematic Review on Cannabis Hyperemesis Syndrome and Its Management Options.Medical principles and practice : international journal of the Kuwait University, Health Science Centre
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Topical Capsaicin for Treating Cannabinoid Hyperemesis Syndrome.Case reports in gastrointestinal medicine · 2020
    Article
  6. Review
  7. Cannabinoid Hyperemesis.Medical cannabis and cannabinoids · 2019
    Review
  8. Article
  9. In Response to Letter to the Editor Regarding: Cannabinoid Hyperemesis Syndrome: Diagnosis, Pathophysiology, and Treatment-a Systematic Review.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2017
    Article
  10. Article
  11. Cannabis Hyperemesis Syndrome: What Do We Know?Medical cannabis and cannabinoids
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Faisal InayatNew York-Presbyterian Hospital, Weill Cornell Medical College, New York, New York, USA.
Hafeez Ul Hassan VirkMount Sinai St. Luke's Hospital, Icahn School of Medicine, New York, New York, USA.
Waqas UllahUniversity of Arizona, Tucson, Arizona, USA.
Qulsoom HussainShifa International Hospital, Islamabad, Pakistan.
Cornell University · USShifa International Hospital · PKSt. Luke's Hospital · USUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabinoid hyperemesis syndrome (CHS) is a rare clinical syndrome characterised by nausea, cyclic vomiting and severe abdominal pain in association with chronic cannabis use. It is often under-recognised or misdiagnosed, resulting in the unnecessary workup and frequent hospitalisations. Long-term treatment of CHS is abstinence from cannabis, but acute symptomatic management has been a struggle for many clinicians. The present report highlights the use of haloperidol as an agent that successfully and safely treats the unrelenting symptoms of CHS.

Indexed as

AdultAntiemeticsCannabinoidsHaloperidolHumansMaleMarijuana AbuseNauseaSyndromeTreatment OutcomeVomitingAntiemeticsCannabinoidsHaloperidol

Identifiers

PMID28052951
PMCPMC5256592
OpenAlexW2568731522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.