Evidence map›Paper›PMID 28052910›Full record

Trial reportBMJ open2017

Acupuncture and PC6 stimulation for the prevention of postoperative nausea and vomiting in patients undergoing elective laparoscopic resection of colorectal cancer: a study protocol for a three-arm randomised pilot trial.

Kun Hyung Kim, Dae Hun Kim, Ji Min Bae, Gyung Mo Son, Kyung Hee Kim, Seung Pyo Hong, Gi Young Yang, Hee Young Kim

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02509143 (High-dose Acupuncture for Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Colorectal Surgery), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02509143 nacompletednot on this map

High-dose Acupuncture for Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Colorectal Surgery: A Randomized Controlled Pilot Study

TypeinterventionalSponsorPusan National University Yangsan HospitalRan2015 to 2016Enrolled60ConditionsPostoperative Nausea and Vomiting, Colorectal NeoplasmsArmsHigh-dose acupuncture with intravenous infusion of ramosetron, P6 stimulation with intravenous infusion of ramosetron, Intravenous infusion of ramosetron
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kun Hyung KimSchool of Korean Medicine, Pusan National University, Yangsan, South Korea.
Dae Hun KimDepartment of Acupuncture & Moxibustion, Korean Medicine Hospital, Pusan National University, Yangsan, South Korea.
Ji Min BaeDepartment of Acupuncture & Moxibustion, Korean Medicine Hospital, Pusan National University, Yangsan, South Korea.
Gyung Mo SonDepartment of Surgery, Pusan National University Yangsan Hospital, Yangsan, South Korea.
Kyung Hee KimDepartment of Surgery, Pusan National University Yangsan Hospital, Yangsan, South Korea.
Seung Pyo HongDepartment of Acupuncture & Moxibustion, Korean Medicine Hospital, Pusan National University, Yangsan, South Korea.
Gi Young YangSchool of Korean Medicine, Pusan National University, Yangsan, South Korea.
Hee Young KimDepartment of Anesthesia and Pain Medicine, Pusan National University Yangsan Hospital, Yangsan, South Korea.
Pusan National University Yangsan Hospital · KRPusan National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aims to assess the feasibility of acupuncture and a Pericardium 6 (PC6) wristband as an add-on intervention of antiemetic medication for the prevention of postoperative nausea and vomiting (PONV) in patients undergoing elective laparoscopic colorectal cancer resection. METHODS AND ANALYSIS: A total of 60 participants who are scheduled to undergo elective laparoscopic resection of colorectal cancer will be recruited. An enhanced recovery after surgery protocol using standardised antiemetic medication will be provided for all participants. Participants will be equally randomised into acupuncture plus PC6 wristband (Acupuncture), PC6 wristband alone (Wristband), or no acupuncture or wristband (Control) groups using computer-generated random numbers concealed in opaque, sealed, sequentially numbered envelopes. For the acupuncture combined with PC6 wristband group, the embedded auricular acupuncture technique for preoperative anxiolysis and up to three sessions of acupuncture treatments with manual and electrical stimulation within 48 hours after surgery will be provided by qualified Korean medicine doctors. The PC6 wristband will be applied in the Acupuncture and Wristband groups, beginning 1 hour before surgery and lasting 48 hours postoperatively. The primary outcome will be the number of participants who experience moderate or severe nausea, defined as nausea at least 4 out of 10 on a severity numeric rating scale or vomiting at 24 hours after surgery. Secondary outcomes, including symptom severity, participant global assessments and satisfaction, quality of life, physiological recovery, use of medication and length of hospital stay, will be assessed. Adverse events and postoperative complications will be measured for 1 month after surgery. ETHICS AND DISSEMINATION: All participants will provide written informed consent. The study has been approved by the institutional review board (IRB). This pilot trial will inform a full-scale randomised trial of acupuncture combined with PC6 stimulation for the prevention of PONV in patients undergoing elective laparoscopic colorectal cancer surgery. TRIAL REGISTRATION NUMBER: NCT02509143.

Indexed as

Research DesignAcupuncture PointsAcupuncture TherapyAdolescentAdultAgedAged, 80 and overAntiemeticsColorectal NeoplasmsElective Surgical ProceduresHumansLaparoscopyLength of StayMiddle AgedPatient SatisfactionPilot ProjectsAntiemeticsacupuncturecolorectal canceromplementary and alternative medicinepostoperative nausea and vomiting

Identifiers

PMID28052910
PMCPMC5223651
OpenAlexW2568479107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.