Evidence map›Paper›PMID 28052888›Full record

Observational studyThe American journal of clinical nutrition2017

Food insecurity, but not HIV-infection status, is associated with adverse changes in body composition during lactation in Ugandan women of mixed HIV status.

Elizabeth M Widen, Shalean M Collins, Hijab Khan, Claire Biribawa, Daniel Acidri, Winifred Achoko, Harriet Achola, Shibani Ghosh, Jeffrey K Griffiths, Sera L Young

2 registry-linked trialsAbstract readObservational Study
In one paragraph

Observational study in The American journal of clinical nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02922829 completednot on this map

The PreNAPS Study: Food Insecurity, Prenatal Nutrition, and Psychosocial Health Outcomes Among HIV Infected and Uninfected Pregnant Women Attending ANC Services at Gulu Regional Referral Hospital

TypeobservationalSponsorNorthwestern UniversityRan2013 to 2014Enrolled403ConditionsHIV, Pregnancy
NCT02925429 completednot on this map

The PostNAPS Study: Food Insecurity As A Major Determinant of Poor Nutritional and Psychosocial Health Outcomes Among HIV-Infected and -Uninfected Lactating Women and Their Infants in Gulu, Northern Uganda.

TypeobservationalSponsorNorthwestern UniversityRan2013 to 2015Enrolled246ConditionsFood Insecurity, HIV, Maternal and Child Health, Nutrition
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elizabeth M WidenInstitute of Human Nutrition, Department of Epidemiology and Medicine, New York Obesity Research Center, Columbia University Medical Center, New York, NY.
Shalean M CollinsDepartment of Population Medicine, Program in International Nutrition, Cornell University, Ithaca, NY.
Hijab KhanDepartment of Biology, Cornell University, Ithaca, NY.
Claire BiribawaPrenatal Nutrition and Psychosocial Health Outcomes Study Uganda, Gulu, Uganda; and.
Daniel AcidriPrenatal Nutrition and Psychosocial Health Outcomes Study Uganda, Gulu, Uganda; and.
Winifred AchokoPrenatal Nutrition and Psychosocial Health Outcomes Study Uganda, Gulu, Uganda; and.
Harriet AcholaPrenatal Nutrition and Psychosocial Health Outcomes Study Uganda, Gulu, Uganda; and.
Shibani GhoshFriedman School of Nutrition Science and Policy and.
Jeffrey K GriffithsFriedman School of Nutrition Science and Policy and.
Sera L YoungDepartment of Population Medicine, Program in International Nutrition, Cornell University, Ithaca, NY; sera.young@northwestern.edu.

Funding

Scientific & Technical CoreP2CHD042849 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI MARK D. HAYWARD · 2017 to 2026
$5.2M
OBESITY RESEARCH CENTER TRAINING PROGRAMT32DK007559 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI DYMPNA GALLAGHER · 1989 to 2026
$4.3M
Pregnancy weight trajectories and offspring adiposityR00HD086304 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI WIDEN, ELIZABETH MARIE · 2018 to 2020
$744k
Pregnancy weight trajectories and offspring adiposityK99HD086304 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI WIDEN, ELIZABETH MARIE · 2016 to 2017
$258k
NICHD NIH HHS K99 HD086304NICHD NIH HHS P2C HD042849NICHD NIH HHS R00 HD086304NIDDK NIH HHS T32 DK007559
6 · The paper itself

Abstract

backgroundBody composition is an important indicator of nutritional status and health. How body composition changes during 12 mo of breastfeeding in HIV-infected women receiving antiretroviral therapy (ART) is unknown.

objectiveWe assessed whether HIV or food insecurity was associated with adverse postpartum body-composition changes in Ugandan women.

designA cohort of 246 women [36.5% of whom were HIV positive (HIV+) and were receiving ART] were followed to 12 mo postpartum. Repeated measures included weight, fat mass, fat-free mass, midupper arm circumference, triceps skinfold thickness [which allowed for the derivation of arm muscle area (AMA) and arm fat area (AFA)], breastfeeding, and individual food insecurity. Longitudinal regression models were constructed to assess associations between HIV and food insecurity and changes in body composition over time.

resultsAt baseline, HIV+ women compared with HIV-negative women had a higher mean ± SD food-insecurity score (11.3 ± 5.5 compared with 8.6 ± 5.5, respectively; P < 0.001) and lower AMA (40.6 ± 5.7 compared with 42.9 ± 6.9 cm

conclusionsBody-composition changes are minimal during lactation. HIV is not associated with body composition; however, food insecurity is associated with changes in body composition during lactation. This trial was registered at clinicaltrials.gov as NCT02922829 and NCT02925429.

Indexed as

Body CompositionFood SupplyLactationNutritional StatusAdiposityAdultBody Mass IndexBody WeightBreast FeedingCohort StudiesFemaleHIV InfectionsHumansLongitudinal StudiesMaternal Nutritional Physiological PhenomenaPostpartum PeriodBMIbody compositionpostpartumpregnancyUganda

Identifiers

PMID28052888
PMCPMC5267304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.