ArticleAmerican journal of physiology. Renal physiology2017
Fgfr2 is integral for bladder mesenchyme patterning and function.
Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- New insights into interstitial cystitis/bladder pain syndrome at single-cell resolution.BJUI compass · 2025Review
- Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter.Development (Cambridge, England) · 2025Article
- Transcription factor Tcf21 modulates urinary bladder size and differentiation.Development, growth & differentiation · 2024Article
- New developments in the biology of fibroblast growth factors.WIREs mechanisms of disease · 2022Review
- Single-cell and spatial analysis reveal interaction of FAPNature communications · 2022Article
- Osr1 Is Required for Mesenchymal Derivatives That Produce Collagen in the Bladder.International journal of molecular sciences · 2021Article
- Loss of Fibroblast Growth Factor Receptor 2 (FGFR2) Leads to Defective Bladder Urothelial Regeneration after Cyclophosphamide Injury.The American journal of pathology · 2021Article
- FGF/FGFR signaling in health and disease.Signal transduction and targeted therapy · 2020Review
- LIM homeodomain transcription factor Isl1 affects urethral epithelium differentiation and apoptosis via Shh.Cell death & disease · 2019Article
- Non-invasive voiding assessment in conscious mice.Bladder (San Francisco, Calif.) · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
While urothelial signals, including sonic hedgehog (Shh), drive bladder mesenchyme differentiation, it is unclear which pathways within the mesenchyme are critical for its development. Studies have shown that fibroblast growth factor receptor 2 (Fgfr2) is necessary for kidney and ureter mesenchymal development. Our objective was to determine the role of Fgfr2 in bladder mesenchyme. We used
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.