Evidence map›Paper›PMID 28052850›Full record

ArticleAntimicrobial agents and chemotherapy2017

Association between Polymorphisms in the Pf

Mathieu Gendrot, Silman Diawara, Marylin Madamet, Mame Bou Kounta, Sébastien Briolant, Khalifa Ababacar Wade, Mansour Fall, Nicolas Benoit, Aminata Nakoulima, Rémy Amalvict and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Mathieu GendrotUnité de Parasitologie et d'Entomologie, Département des Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, Marseille, France.
Silman DiawaraLaboratoire d'étude de la chimiosensibilité du paludisme, Fédération des laboratoires, Hôpital Principal de Dakar, Dakar, Senegal.
Marylin MadametAix Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UM 63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France.
Mame Bou KountaService des Urgences, Hôpital Principal de Dakar, Dakar, Senegal.
Sébastien BriolantUnité de Parasitologie et d'Entomologie, Département des Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, Marseille, France.
Khalifa Ababacar WadeService des Urgences, Hôpital Principal de Dakar, Dakar, Senegal.
Mansour FallService de Réanimation Médicale, Hôpital Principal de Dakar, Dakar, Senegal.
Nicolas BenoitAix Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UM 63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France.
Aminata NakoulimaService de Pédiatrie, Hôpital Principal de Dakar, Dakar, Senegal.
Rémy AmalvictAix Marseille Université, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UM 63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France.
Yaya DiéméLaboratoire d'étude de la chimiosensibilité du paludisme, Fédération des laboratoires, Hôpital Principal de Dakar, Dakar, Senegal.
Bécaye FallLaboratoire d'étude de la chimiosensibilité du paludisme, Fédération des laboratoires, Hôpital Principal de Dakar, Dakar, Senegal.
Boubacar WadeChefferie, Hôpital Principal de Dakar, Dakar, Senegal.
Bakary DiattaService de Réanimation Médicale, Hôpital Principal de Dakar, Dakar, Senegal.
Bruno PradinesUnité de Parasitologie et d'Entomologie, Département des Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, Marseille, France bruno.pradines@gmail.com.
Hôpital Principal de Dakar · SNInserm · FRInstitut de Médecine Tropicale du Service de Santé des Armées · FRAix-Marseille Université · FRUnité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymorphisms and the overexpression of transporter genes, especially of the ATP-binding cassette superfamily, have been involved in antimalarial drug resistance. The objective of this study was to use 77 Senegalese

Indexed as

Polymorphism, GeneticAmodiaquineAntimalarialsArtemisininsArtesunateAsparagineATP-Binding Cassette TransportersChloroquineDoxycyclineDrug ResistanceEthanolaminesFluorenesGene ExpressionHumansInhibitory Concentration 50LumefantrineAmodiaquineAntimalarialsArtemisininsartenimolArtesunateAsparagineATP-Binding Cassette TransportersChloroquinedesethylamodiaquineDoxycyclineEthanolaminesFluorenesLumefantrinemdr gene protein, PlasmodiumMefloquineNaphthyridinespiperaquinePiperazinesProtein IsoformsProtozoan ProteinspyronaridineQuinineQuinolinesantimalarial drugin vitromalariamolecular markerPlasmodium falciparumresistance

Identifiers

PMID28052850
PMCPMC5328570
OpenAlexW2571006825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.