Evidence map›Paper›PMID 28052764›Full record

ArticleMolecular brain2017

Tat-HSP22 inhibits oxidative stress-induced hippocampal neuronal cell death by regulation of the mitochondrial pathway.

Hyo Sang Jo, Dae Won Kim, Min Jea Shin, Su Bin Cho, Jung Hwan Park, Chi Hern Lee, Eun Ji Yeo, Yeon Joo Choi, Hyeon Ji Yeo, Eun Jeong Sohn and 8 more

Open access · goldAbstract read
In one paragraph

Article in Molecular brain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Protection against HTranslational neuroscience · 2022
    Article
  8. Review
  9. Morroniside protects OLN-93 cells against HCell cycle (Georgetown, Tex.) · 2021
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Hyo Sang JoDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea.
Dae Won KimDepartment of Biochemistry and Molecular Biology, Research Institute of Oral Sciences, College of Dentistry, Gangneung-Wonju National University, Gangneung, 25457, Korea.
Min Jea ShinDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea.
Su Bin ChoDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea.
Jung Hwan ParkDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea.
Chi Hern LeeDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea.
Eun Ji YeoDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea.
Yeon Joo ChoiDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea.
Hyeon Ji YeoDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea.
Eun Jeong SohnDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea.
Ora SonDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea.
Sung-Woo ChoDepartment of Biochemistry and Molecular Biology, University of Ulsan College of Medicine, Seoul, 05505, Korea.
Duk-Soo KimDepartment of Anatomy, College of Medicine, Soonchunhyang University, Cheonan-Si, 31538, Korea.
Yeon Hee YuDepartment of Anatomy, College of Medicine, Soonchunhyang University, Cheonan-Si, 31538, Korea.
Keun Wook LeeDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea.
Jinseu ParkDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea.
Won Sik EumDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea. wseum@hallym.ac.kr.
Soo Young ChoiDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chuncheon, 24252, Korea. sychoi@hallym.ac.kr.
Hallym University · KRSoonchunhyang University · KRGangneung–Wonju National University · KRUlsan College · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress plays an important role in the progression of various neuronal diseases including ischemia. Heat shock protein 22 (HSP22) is known to protect cells against oxidative stress. However, the protective effects and mechanisms of HSP22 in hippocampal neuronal cells under oxidative stress remain unknown. In this study, we determined whether HSP22 protects against hydrogen peroxide (H

Indexed as

AnimalsCell DeathCell Membrane PermeabilityGene Products, tatGerbillinaeHeat-Shock ProteinsHippocampusHydrogen PeroxideMaleMembrane Potential, MitochondrialMitochondriaMolecular ChaperonesNeuronsNeuroprotective AgentsOxidative StressProtein Serine-Threonine KinasesGene Products, tatHeat-Shock ProteinsHSPB8 protein, humanHydrogen PeroxideMolecular ChaperonesNeuroprotective AgentsProtein Serine-Threonine KinasesRecombinant Fusion ProteinsApoptosisIschemiaOxidative stressProtein therapyTat-HSP22

Identifiers

PMID28052764
PMCPMC5210279
OpenAlexW2571295442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.