ArticleJournal of neurotrauma2017
Tripartite Stratification of the Glasgow Coma Scale in Children with Severe Traumatic Brain Injury and Mortality: An Analysis from a Multi-Center Comparative Effectiveness Study.
Article in Journal of neurotrauma, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Presenting Characteristics Associated With Outcome in Children With Severe Traumatic Brain Injury: A Secondary Analysis From a Randomized, Controlled Trial of Therapeutic Hypothermia.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2018Trial
- Paediatric traumatic brain injury: unique population and unique challenges.Brain : a journal of neurology · 2026Review
- Analgesia, Sedation, and Neuromuscular Blockade in Pediatric Severe Traumatic Brain Injury: Secondary Analysis of the "Approaches and Decisions in Acute Pediatric TBI Trial" (ADAPT).Neurocritical care · 2025Observational
- Neuromonitoring in Children with Traumatic Brain Injury.Neurocritical care · 2024Review
- New Insights into the Diagnosis and Age Determination of Retinal Hemorrhages from Abusive Head Trauma: A Systematic Review.Diagnostics (Basel, Switzerland) · 2023Review
- Correlation between intracranial pressure monitoring for severe traumatic brain injury with hospital length of stay and discharge disposition: a retrospective observational cohort study.Patient safety in surgery · 2022Article
- Effects of inpatient rehabilitation after acute care on functional and quality-of-life outcomes in children with severe traumatic brain injury.Brain injury · 2022Observational
- Comparative Effectiveness of Diversion of Cerebrospinal Fluid for Children With Severe Traumatic Brain Injury.JAMA network open · 2022Observational
- Characteristics Associated with the Use of an Inpatient Rehabilitation or Skilled Nursing Facility after Acute Care in Children with Severe Traumatic Brain Injury.Developmental neurorehabilitation · 2021Observational
- Novel in vivo depiction of optic nerves hemorrhages in child abuse: a 3D-SWI pilot study.Neuroradiology · 2021Article
- Assessment of Dynamic Intracranial Compliance in Children with Severe Traumatic Brain Injury: Proof-of-Concept.Neurocritical care · 2021Article
- Predictors of intracranial hypertension in children undergoing ICP monitoring after severe traumatic brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Latent Class Analysis to Classify Injury Severity in Pediatric Traumatic Brain Injury.Journal of neurotrauma · 2020Article
- Ability of the PILOT score to predict 6-month functional outcome in pediatric patients with moderate-severe traumatic brain injury.Journal of pediatric surgery · 2020Observational
- Intracranial pressure monitoring associated with increased mortality in pediatric brain injuries.Pediatric surgery international · 2020Article
- Addressing Key Clinical Care and Clinical Research Needs in Severe Pediatric Traumatic Brain Injury: Perspectives From a Focused International Conference.Frontiers in pediatrics · 2020Review
- Effects of salvianolic acid on cerebral perfusion in patients after acute stroke: A single-center randomized controlled trial.Experimental and therapeutic medicine · 2018Article
- Pediatric Neurocritical Care and Neuromonitoring in 2018-Maybe We Need to Go Back to the Basics?Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2018Article
- Challenges and opportunities for pediatric severe TBI-review of the evidence and exploring a way forward.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Glasgow Coma Scale (GCS) score has not been validated in children younger than 5 years and the clinical circumstances at the time of assignment can limit its applicability. This study describes the distribution of GCS scores in the population, the relationship between injury characteristics with the GCS score, and the association between the tripartite stratification of the GCS on mortality in children with severe traumatic brain injury (TBI). The first 200 children from a multi-center comparative effectiveness study in severe TBI (inclusion criteria: age 0-18 years, GCS ≤8 at the time of intracranial pressure [ICP] monitoring) were analyzed. After tripartite stratification of GCS scores (Group A, GCS 3; Group B, GCS 4 - 5; and Group C, GCS 6 - 8), analyses of variance and chi-square testing were performed. Mean age was 7.61 years ±5.33 and mortality was 19.1%. There was no difference in etiology or type/mechanism of injury between groups. However, groups demonstrated differences in neuromuscular blockade, endotracheal intubation, pre-hospital events (cardiac arrest and apnea), coagulopathy, and pupil response. Mortality between groups was different (42.2% Group A, 22.6% Group B, and 3.8% Group C;
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