Evidence map›Paper›PMID 28052353›Full record

ReviewBioEssays : news and reviews in molecular, cellular and developmental biology2017

Temporal and spatial regulation of mRNA export: Single particle RNA-imaging provides new tools and insights.

Stephanie Heinrich, Carina Patrizia Derrer, Azra Lari, Karsten Weis, Ben Montpetit

Abstract readReview
In one paragraph

Review in BioEssays : news and reviews in molecular, cellular and developmental biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Frontiers in genetics · 2019
    Review
  15. Live-Cell Imaging of mRNP-NPC Interactions in Budding Yeast.Methods in molecular biology (Clifton, N.J.) · 2019
    Article
  16. Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephanie HeinrichInstitute of Biochemistry, ETH Zurich, Zurich, Switzerland.
Carina Patrizia DerrerInstitute of Biochemistry, ETH Zurich, Zurich, Switzerland.
Azra LariDepartment of Cell Biology, University of Alberta, Edmonton, Canada.
Karsten WeisInstitute of Biochemistry, ETH Zurich, Zurich, Switzerland.
Ben MontpetitDepartment of Cell Biology, University of Alberta, Edmonton, Canada.

Funding

Structure and function of the nuclear pore complexR01GM058065 · NIGMS · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI HEALD, REBECCA W · 1998 to 2015
$4.6M
Mechanisms of gene-specific and genome-wide regulation of mRNA turnoverR01GM101257 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI THORNER, JEREMY W. · 2013 to 2016
$1.2M
NIGMS NIH HHS R01 GM058065NIGMS NIH HHS R01 GM101257
6 · The paper itself

Abstract

The transport of messenger RNAs (mRNAs) from the nucleus to cytoplasm is an essential step in the gene expression program of all eukaryotes. Recent technological advances in the areas of RNA-labeling, microscopy, and sequencing are leading to novel insights about mRNA biogenesis and export. This includes quantitative single molecule imaging (SMI) of RNA molecules in live cells, which is providing knowledge of the spatial and temporal dynamics of the export process. As this information becomes available, it leads to new questions, the reinterpretation of previous findings, and revised models of mRNA export. In this review, we will briefly highlight some of these recent findings and discuss how live cell SMI approaches may be used to further our current understanding of mRNA export and gene expression.

Indexed as

RNA TransportAnimalsCell NucleusGene Expression RegulationHumansNuclear PoreRNA, MessengerSaccharomyces cerevisiaeSingle Molecule ImagingRNA, Messengerin vivo single molecule imagingmRNA exportMS2-MCP systemnuclear pore complexPP7-PCP systemRNA-binding protein

Identifiers

PMID28052353
PMCPMC5992323

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.