ArticleScientific reports2017
Universal and reusable virus deactivation system for respiratory protection.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04465604 (HYPERTONIC SALINE COATED FACE MASK FOR REDUCING RESPIRATORY SYMPTOM SEVERITY IN PATIENTS WITH COVID-19), which is not on this map. Cited by 49 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Hypertonic saline coated face mask for reducing respiratory symptom severity in patients with covid-19
Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Conservation Practices for Personal Protective Equipment: A Systematic Review with Focus on Lower-Income Countries.International journal of environmental research and public health · 2023Pooled it
- Decontamination interventions for the reuse of surgical mask personal protective equipment: a systematic review.The Journal of hospital infection · 2020Pooled it
- Evaluating layer contributions and salt coating effects on mask performance.RSC advances · 2024Article
- Functionalization of Polymer-Wrapped Silver Nanoclusters and Potential Applications as Antimicrobial Mask Materials.ACS omega · 2023Article
- Inactivation of SARS-CoV-2 on salt-coated surfaces: an in vitro study.Archives of microbiology · 2023Article
- Saline nasal irrigation and gargling in COVID-19: a multidisciplinary review of effects on viral load, mucosal dynamics, and patient outcomes.Frontiers in public health · 2023Review
- In vitro testing of salt coating of fabrics as a potential antiviral agent in reusable face masks.Scientific reports · 2022Article
- Advances in nanotechnology application in biosafety materials: A crucial response to COVID-19 pandemic.Biosafety and health · 2022Review
- Salt and surfactant coated filters with antiviral properties and low pressure drop for prospective SARS-CoV2 applications.Scientific reports · 2022Article
- Development of saline loaded mask materials, evaluation of the antimicrobial efficacy and survivability of selected bacteria on these mask materials.Journal of King Saud University. Science · 2022Article
- Virucidal N95 Respirator Face Masks via Ultrathin Surface-Grafted Quaternary Ammonium Polymer Coatings.ACS applied materials & interfaces · 2022Article
- Face masks to fight against COVID-19 pandemics: A comprehensive review of materials, design, technology and product development.Journal of industrial textiles · 2022Review
- An overview of solutions for airborne viral transmission reduction related to HVAC systems including liquid desiccant air-scrubbing.Energy (Oxford, England) · 2022Article
- Antiviral/antibacterial biodegradable cellulose nonwovens as environmentally friendly and bioprotective materials with potential to minimize microplastic pollution.Journal of hazardous materials · 2022Article
- Masks for COVID-19.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Review
- What do masks mask? A study on transdermal COMedical engineering & physics · 2021Article
- Biodegradable and multifunctional surgical face masks: A brief review on demands during COVID-19 pandemic, recent developments, and future perspectives.The Science of the total environment · 2021Review
- Impacts of COVID-19 Outbreak on the Municipal Solid Waste Management: Now and beyond the Pandemic.ACS environmental Au · 2021Review
- Functionalized Masks: Powerful Materials against COVID-19 and Future Pandemics.Small (Weinheim an der Bergstrasse, Germany) · 2021Review
- Public Health Messages About Face Masks Early in the COVID-19 Pandemic: Perceptions of and Impacts on Canadians.Journal of community health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aerosolized pathogens are a leading cause of respiratory infection and transmission. Currently used protective measures pose potential risk of primary/secondary infection and transmission. Here, we report the development of a universal, reusable virus deactivation system by functionalization of the main fibrous filtration unit of surgical mask with sodium chloride salt. The salt coating on the fiber surface dissolves upon exposure to virus aerosols and recrystallizes during drying, destroying the pathogens. When tested with tightly sealed sides, salt-coated filters showed remarkably higher filtration efficiency than conventional mask filtration layer, and 100% survival rate was observed in mice infected with virus penetrated through salt-coated filters. Viruses captured on salt-coated filters exhibited rapid infectivity loss compared to gradual decrease on bare filters. Salt-coated filters proved highly effective in deactivating influenza viruses regardless of subtypes and following storage in harsh environmental conditions. Our results can be applied in obtaining a broad-spectrum, airborne pathogen prevention device in preparation for epidemic and pandemic of respiratory diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.