ArticleScientific reports2017
Impacts of canine distemper virus infection on the giant panda population from the perspective of gut microbiota.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- The Commensal Microbiota and Viral Infection: A Comprehensive Review.Frontiers in immunology · 2019Pooled it
- Safeguarding a Flagship Species: Integrated Surveillance of Cross-Species Pathogen Transmission in Giant Panda Ecosystems.Ecology and evolution · 2026Review
- Effects and Mechanisms of Lactiplantibacillus plantarum G83 on Enterotoxigenic Escherichia coli (ETEC)-Induced Intestinal Inflammation.Probiotics and antimicrobial proteins · 2026Article
- The golden jackal (Canis aureus): interaction of fur and fecal microbiota, host genetics and animal traits.Animal microbiome · 2025Article
- Fecal Microbiota Changes in Angus Beef Cows Persistently Infected by Bovine Viral Diarrhea Virus.Veterinary sciences · 2025Article
- The Detection of Mixed Infection with Canine Parvovirus, Canine Distemper Virus, and Rotavirus in Giant Pandas by Multiplex PCR.Veterinary sciences · 2025Article
- The giant panda gut harbors a high diversity of lactic acid bacteria revealed by a novel culturomics pipeline.mSystems · 2024Article
- Unraveling the antimicrobial potential ofFrontiers in microbiology · 2024Article
- Fecal microbiota of the synanthropic golden jackal (Canis aureus).Animal microbiome · 2023Article
- Diagnosis and surgical management of testicular seminoma in captive giant panda (Ailuropoda melanoleuca).Veterinary and animal science · 2023Article
- The putative maintaining mechanism of gut bacterial ecosystem in giant pandas and its potential application in conservation.Evolutionary applications · 2023Article
- Surveillance Study ofAntibiotics (Basel, Switzerland) · 2022Article
- Comparative transcriptome analyses of immune responses to LPS in peripheral blood mononuclear cells from the giant panda, human, mouse, and monkey.Frontiers in genetics · 2022Article
- Review
- Endophytic bacterial community diversity in two citrus cultivars with different citrus canker disease resistance.Archives of microbiology · 2021Article
- Diversity and Composition of Gut Bacterial Community in Giant Panda with Anorexia.Current microbiology · 2021Article
- Higher Prevalence of Extended-Spectrum Cephalosporin-ResistantAntibiotics (Basel, Switzerland) · 2021Article
- Impact of host intraspecies genetic variation, diet, and age on bacterial and fungal intestinal microbiota in tigers.MicrobiologyOpen · 2020Article
- Canine Distemper Virus (CDV) Transit Through the Americas: Need to Assess the Impact of CDV Infection on Species Conservation.Frontiers in microbiology · 2020Article
- Adenovirus infection is associated with altered gut microbial communities in a non-human primate.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recent increase in infectious disease outbreaks has been directly linked to the global loss of biodiversity and the decline of some endangered species populations. Between December 2014 and March 2015, five captive giant pandas died due to canine distemper virus (CDV) infection in China. CDV has taken a heavy toll on tigers and lions in recent years. Here, we describe the first gut microbiome diversity study of CDV-infected pandas. By investigating the influence of CDV infection on gut bacterial communities in infected and uninfected individuals and throughout the course of infection, we found that CDV infection distorted the gut microbiota composition by reducing the prevalence of the dominant genera, Escherichia and Clostridium, and increasing microbial diversity. Our results highlight that increases in intestinal inflammation and changes in the relative abundances of pathogen-containing gut communities occur when individuals become infected with CDV. These results may provide new insights into therapeutics that target the microbiota to attenuate the progression of CDV disease and to reduce the risk of gut-linked disease in individuals with CDV. In addition, our findings underscore the need for better information concerning the dynamics of infection and the damage caused by pathogens in panda populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.