Evidence map›Paper›PMID 28050846›Full record

ArticleAMB Express2017

Optimization of medium compositions to improve a novel glycoprotein production by Streptomyces kanasenisi ZX01.

Yong Zhou, Yu-Bo Sun, Hong-Wei He, Jun-Tao Feng, Xing Zhang, Li-Rong Han

Abstract read
In one paragraph

Article in AMB Express, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yong ZhouResearch and Development Center of Biorational Pesticides, Northwest A & F University, Yangling, 712100, Shaanxi, China.
Yu-Bo SunResearch and Development Center of Biorational Pesticides, Northwest A & F University, Yangling, 712100, Shaanxi, China.
Hong-Wei HeResearch and Development Center of Biorational Pesticides, Northwest A & F University, Yangling, 712100, Shaanxi, China.
Jun-Tao FengResearch and Development Center of Biorational Pesticides, Northwest A & F University, Yangling, 712100, Shaanxi, China.
Xing ZhangResearch and Development Center of Biorational Pesticides, Northwest A & F University, Yangling, 712100, Shaanxi, China. zhxing1952@gmail.com.
Li-Rong HanResearch and Development Center of Biorational Pesticides, Northwest A & F University, Yangling, 712100, Shaanxi, China. hlr4119@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Streptomyces kanasenisi ZX01 was found to produce a novel glycoprotein GP-1 previously, which was secreted into medium and had significant activity against tobacco mosaic virus. However, the low production of GP-1 by strain ZX01 limited its further studies. In order to improve the yield of GP-1, a series of statistical experimental design methods were applied to optimize medium of strain ZX01 in this work. Millet medium was chosen to be the optimal original medium for optimization. Soluble starch and yeast extract were identified as the optimal carbon and nitrogen source using one-factor-at-a-time method. Response surface methodology was used to optimize medium compositions (soluble starch, yeast extract and inorganic salts). A higher yield of GP-1 was 601.33 µg/L after optimization. The optimal compositions of medium were: soluble starch 13.61 g/L, yeast extract 4.19 g/L, NaCl 3.54 g/L, CaCO

Indexed as

Anti-TMVGlycoproteinOptimizationResponse surface methodologyStreptomyces

Identifiers

PMID28050846
PMCPMC5209317

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.