Evidence map›Paper›PMID 28050502›Full record

ArticleJournal of clinical and diagnostic research : JCDR2016

Antibacterial Effect of Aloe Vera Gel against Oral Pathogens: An In-vitro Study.

Supreet Jain, Nirav Rathod, Ravleen Nagi, Jaideep Sur, Afshan Laheji, Naveen Gupta, Priyanka Agrawal, Swati Prasad

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.

  1. Pooled it
  2. Therapeutic potential of Aloe vera in diabetes mellitus treatment: an update.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Production ofLife (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Natural antibiotics against antimicrobial resistance: sources and bioinspired delivery systems.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Clinical and Radiographic Evaluation ofInternational journal of clinical pediatric dentistry · 2023
    Article
  14. Article
  15. Review
  16. Extracts ofPharmaceutics · 2022
    Article
  17. Abscisic acid and aloe-emodin against NS2B-NS3A protease of Japanese encephalitis virus.Environmental science and pollution research international · 2022
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Supreet JainSenior Lecturer, Department of Oral Medicine and Radiology, New Horizon Dental College and Research Institute , Bilaspur, Chhattisgarh, India .
Nirav RathodAssistant Professor, Department of Prosthodontics, Chandulal Memorial Medical College , Bhilai, Chhattisgarh, India .
Ravleen NagiReader, Department of Oral Medicine and Radiology, New Horizon Dental College and Research Institute , Bilaspur, Chhattisgarh, India .
Jaideep SurProfessor, Department of Oral Medicine and Radiology, Rungta College of Dental Sciences and Research , Bhilai, Chhattisgarh, India .
Afshan LahejiProfessor and Head, Department of Oral and Maxillofacial Pathology. Daswani Dental College , Kota, Rajasthan, India .
Naveen GuptaPostgraduate Student, Department of Conservative Dentistry and Endodontics, New Horizon Dental College and Research Institute , Bilaspur, Chhattisgarh, India .
Priyanka AgrawalConsultant, Department of Oral Medicine and Radiology, Shradha and Jai Ambe Hospital , Raipur, Chhattisgarh, India .
Swati PrasadSenior Lecturer, Department of Oral Medicine and Radiology, Rungta College of Dental Sciences and Research , Bhilai, Chhattisgarh, India .
Chhattisgarh Dental College & Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNatural herbal remedies have shown promising anti-microbial property and fewer side effects compared to synthetic anti-microbial therapy. Aloe Vera is a medicinal plant used for management of various infections since ancient times as it has anti-inflammatory, anti-microbial, and immune-boosting properties.

aimThe aim of the present study was to determine the anti-microbial and inhibitory activities of various concentration of Aloe Vera Gel (AVG) against oral pathogenic bacteria. MATERIALS AND

methodsSubgingival calculus and aspiration of periapical abscess and periodontal abscess was done in 20 patients and the sample transferred to thioglycolate broth, which was incubated in Mutans Sanguis agar, blood agar and cultured in anaerobic gas chamber. The colonies formed were identified further by gram staining methods and biochemical fermentation tests (IMViC). Each isolated colony of identified bacteria were cultured separately in Muller-Hilton broth and incubated at 37°C for 24 hours. Anti-microbial activity of the AVG was tested by the disc diffusion method and minimum inhibitory concentration was determined by broth micro-dilution method.

resultVarious staining and biochemical tests confirmed that the sample contained

conclusionAVG at higher concentration showed anti-bacterial property and can be used as a promising adjunct for oral health care.

Indexed as

Anti-microbialCultureHerbal

Identifiers

PMID28050502
PMCPMC5198455
OpenAlexW2560074788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.