Evidence map›Paper›PMID 28050363›Full record

ArticleJournal of clinical and diagnostic research : JCDR2016

First Line Anti-TB Drug Resistance in an Urban Area of Odisha, India.

Dasarathi Das, Prakasini Satapathy, Biswanath Murmu

Abstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dasarathi DasScientist-E, Regional Medical Research Centre , Bhubaneswar, Odisha, India .
Prakasini SatapathySenior Research Fellow, ICMR, Regional Medical Research Centre , Bhubaneswar, Odisha, India .
Biswanath MurmuTechnical Assistant (Research), Regional Medical Research Centre , Bhubaneswar, Odisha, India .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDrug resistance is a major cause for increasing the global burden of Tuberculosis (TB). However in countries with larger geographical areas and different climatic conditions like India the prevalence of drug resistance varies from place to place. Information on anti-TB drug resistance patterns particularly among newly diagnosed cases is crucial for planning an effective TB control program.

aimTo determine the prevalence of resistance against first line anti-TB drugs and Multi Drug Resistance (MDR) in MATERIALS AND

methodsThe prospective study was carried out in National Reference Laboratory (NRL) of Regional Medical Research Centre (RMRC), Bhubaneswar. During this period from January to September 2014, sputum specimens were collected from 850 suspected pulmonary TB patients attending Designated Microscopy Center (DMC) of Capital Hospital, Bhubaneswar, Odisha. Sputum specimens were subjected to Acid Fast Bacilli (AFB) smear microscopy and further processed for isolation on solid Lowenstein Jensen (LJ) medium. Drug Susceptibility Testing (DST) on isolates with first line anti-TB drugs was performed as per Revised National Tuberculosis Control Programe (RNTCP) guidelines.

resultsOut of all the 850 suspected pulmonary TB patients subjected to AFB microscopy and solid LJ culture, isolation of

conclusionThe study reports an unchanged low level of MDR-TB prevalence among new cases in an urban area of Odisha over a decade. This could be due to the success of Directly Observed Treatment Short-course (DOTS) in effective treatment of drug-susceptible TB in the state and non-transmission from primary Drug Resistance (DR) TB cases.

Indexed as

Acid fast bacilliIsoniazidMulti-drug resistant

Identifiers

PMID28050363
PMCPMC5198316

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