Evidence map›Paper›PMID 28050263›Full record

ArticleActa naturae

Peculiarities of Yeasts and Human Telomerase RNAs Processing.

M P Rubtsova, D P Vasilkova, Yu V Naraykina, O A Dontsova

Open access · bronzeAbstract read
PubMed Full text at PMC
In one paragraph

Article in Acta naturae. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Structure ofRNA biology · 2021
    Article
  2. Review
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

M P RubtsovaLomonosov Moscow State University, Chemistry Department, Leninskie gory, 1, bld. 3, Moscow, 119991 , Russia ; Lomonosov Moscow State University, Belozersky Institute of physico-chemical biology, Leninskie gory, 1, bld. 40, Moscow, 119991, Russia.
D P VasilkovaLomonosov Moscow State University, Chemistry Department, Leninskie gory, 1, bld. 3, Moscow, 119991 , Russia.
Yu V NaraykinaSkolkovo Institute of Science and Technology, Skolkovo Innovation Center, bld. 3, Moscow, 143026 , Russia.
O A DontsovaLomonosov Moscow State University, Chemistry Department, Leninskie gory, 1, bld. 3, Moscow, 119991 , Russia ; Lomonosov Moscow State University, Belozersky Institute of physico-chemical biology, Leninskie gory, 1, bld. 40, Moscow, 119991, Russia ; Lomonosov Moscow State University, Faculty of bioengineering and bioinformatics, Leninskie gory, 1, bld. 73, Moscow, 119991, Russia.
Moscow State University · TJLomonosov Moscow State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Telomerase is one of the major components of the telomeres -- linear eukaryotic chromosome ends - maintenance system. Linear chromosomes are shortened during each cell division due to the removal of the primer used for DNA replication. Special repeated telomere sequences at the very ends of linear chromosomes prevent the deletion of genome information caused by primer removal. Telomeres are shortened at each replication round until it becomes critically short and is no longer able to protect the chromosome in somatic cells. At this stage, a cell undergoes a crisis and usually dies. Rare cases result in telomerase activation, and the cell gains unlimited proliferative capacity. Special types of cells, such as stem, germ, embryonic cells and cells from tissues with a high proliferative potential, maintain their telomerase activity indefinitely. The telomerase is inactive in the majority of somatic cells. Telomerase activity

Indexed as

exosomeprocessingsplicing telomerasetelomerase RNAtranscription

Identifiers

PMID28050263
PMCPMC5199203
OpenAlexW2742973548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.