ArticleBMC neuroscience2017
Important modifications by sugammadex, a modified γ-cyclodextrin, of ion currents in differentiated NSC-34 neuronal cells.
Article in BMC neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Effective Perturbations by Phenobarbital onBiomedicines · 2022Article
- Gambierol Blocks a KToxins · 2022Article
- Article
- Evaluation of the Toxicity of Sugammadex in Zebrafish Larvae.Journal of Korean medical science · 2020Article
- Dexamethasone Treatment Increases the Intracellular Calcium Level ThroughInternational journal of molecular sciences · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSugammadex (SGX) is a modified γ-cyclodextrin used for reversal of steroidal neuromuscular blocking agents during general anesthesia. Despite its application in clinical use, whether SGX treatment exerts any effects on membrane ion currents in neurons remains largely unclear. In this study, effects of SGX treatment on ion currents, particularly on delayed-rectifier K
resultsAfter cells were exposed to SGX (30 μM), there was a reduction in the amplitude of I
conclusionsThe treatment of SGX may influence the amplitude and gating of I
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