ArticleBMC neuroscience2017
The variability of motor evoked potential latencies in neurosurgical motor mapping by preoperative navigated transcranial magnetic stimulation.
Article in BMC neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 38 citations in OpenAlex.
- An automated derivative-based method for detection of motor evoked potential onset latencies in multi-muscle transcranial magnetic stimulation studies.Scientific reports · 2026Article
- Superficial Ventral Premotor Pathways to Primary Motor Cortex Shape the Temporal Coordination of Precision Graspinnog.The European journal of neuroscience · 2026Article
- Rapid Multimuscle Cortical Mapping of the Upper Limb: Activity Reveals Intralimb Gradients.The European journal of neuroscience · 2026Article
- Intensity-Dependent Inhibition of Single Pulse TMS on Stretch-Evoked Long-Latency Responses in the Flexor Carpi Radialis.The European journal of neuroscience · 2026Article
- Stratification of Motor Cortex Excitability to Transcranial Stimulation Uncovers Functional Network Differences in Healthy Older Adults as Revealed by Resting State EEG Functional Coupling in Brain Network.Comprehensive Physiology · 2026Article
- Reliability of Motor Evoked Potential Identification in Pediatric Populations.Transcranial magnetic stimulation (2024) · 2025Article
- Analysis of Neuronal Excitability Profiles for Motor-Eloquent Brain Tumor Entities Using nTMS in 800 Patients.Cancers · 2025Article
- Intraoperative glioblastoma surgery-current challenges and clinical trials: An update.Cancer pathogenesis and therapy · 2024Review
- Motor function in multiple sclerosis assessed by navigated transcranial magnetic stimulation mapping.Journal of neurology · 2024Article
- Connectivity defines the distinctive anatomy and function of the hand-knob area.Brain communications · 2024Article
- Preoperative mapping techniques for brain tumor surgery: a systematic review.Frontiers in oncology · 2024Review
- DELMEP: a deep learning algorithm for automated annotation of motor evoked potential latencies.Scientific reports · 2023Article
- Reconstruction of the Corticospinal Tract in Patients with Motor-Eloquent High-Grade Gliomas Using Multilevel Fiber Tractography Combined with Functional Motor Cortex Mapping.AJNR. American journal of neuroradiology · 2023Article
- Selective Stimulus Intensity during Hotspot Search Ensures Faster and More Accurate Preoperative Motor Mapping with nTMS.Brain sciences · 2023Article
- Article
- Assessing the feasibility of mapping the tibialis anterior muscle with navigated transcranial magnetic stimulation in neuro-oncologic patients.Scientific reports · 2022Article
- Article
- Impaired phase synchronization of motor-evoked potentials reflects the degree of motor dysfunction in the lesioned human brain.Human brain mapping · 2022Article
- Characterization of interlimb interaction via transcutaneous spinal stimulation of cervical and lumbar spinal enlargements.Journal of neurophysiology · 2022Article
- Towards a unified neural mechanism for reactive adaptive behaviour.Progress in neurobiology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecording of motor evoked potentials (MEPs) is used during navigated transcranial magnetic stimulation (nTMS) motor mapping to locate motor function in the human brain. However, factors potentially underlying MEP latency variability in neurosurgical motor mapping are vastly unknown. In the context of this study, one hundred brain tumor patients underwent preoperative nTMS-based motor mapping of the tumor hemisphere between 2010 and 2013. Fourteen predefined predictor variables were recorded, and MEP latencies of abductor pollicis brevis muscle (APB), abductor digiti minimi muscle (ADM), and flexor carpi radialis muscle (FCR) were analyzed using linear mixed-effect multiple regression analysis with the forward step-wise model comparison approach.
resultsCommon factors (relevant to APB, ADM, and FCR) for MEP latency variability were gender, most likely due to body height, and antiepileptic drug (AED) intake. Muscle-specific factors (relevant to APB, ADM, or FCR) for MEP latency variability were resting motor threshold (rMT), tumor side, and tumor location.
conclusionsBased on a large cohort of neurosurgical patients, this study provides data on a wide range of clinical factors that may underlie MEP latency variability. The factors that significantly contributed to MEP latency variability should be standardly recorded and taken into consideration during neurosurgical motor mapping.
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