ArticleBMC evolutionary biology2017
Horizontal gene transfer drives the evolution of Rh50 permeases in prokaryotes.
Article in BMC evolutionary biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 20 citations in OpenAlex.
- Unique phylogenies and metabolic adaptations of novel lineage III and comammoxISME communications · 2026Article
- Pyrrolysine Aminoacyl-tRNA Synthetase as a Tool for Expanding the Genetic Code.International journal of molecular sciences · 2025Review
- Tuning tRNAs for improved translation.Frontiers in genetics · 2024Review
- Conjugative plasmids inhibit extracellular electron transfer inFrontiers in microbiology · 2023Article
- Nutrient Limitation Causes Differential Expression of Transport- and Metabolism Genes in the Compartmentalized Anammox BacteriumFrontiers in microbiology · 2020Article
- Gene tree species tree reconciliation with gene conversion.Journal of mathematical biology · 2019Article
- Complete nitrification: insights into the ecophysiology of comammox Nitrospira.Applied microbiology and biotechnology · 2019Review
- Horizontal Gene Transfer Building Prokaryote Genomes: Genes Related to Exchange Between Cell and Environment are Frequently Transferred.Journal of molecular evolution · 2018Article
- tRNARNA biology · 2018Review
- phylo-node: A molecular phylogenetic toolkit using Node.js.PloS one · 2017Article
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1 author at 1 institution in 1 country.
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Abstract
backgroundRh50 proteins belong to the family of ammonia permeases together with their Amt/MEP homologs. Ammonia permeases increase the permeability of NH
resultsHere, a molecular phylogenetic approach suggests horizontal gene transfer (HGT) as a primary force driving the evolution and spread of RH50 among prokaryotes. In addition, the taxonomic distribution of the RH50 gene among prokaryotes turned out to be very narrow; a single-copy RH50 is present in the genome of only a small proportion of Bacteria, and, first evidence to date, in only three methanogens among Euryarchaea. The coexistence of RH50 and AMT in prokaryotes seems also a rare event. Finally, phylogenetic analyses were used to reconstruct the HGT network along which prokaryotic RH50 evolution has taken place.
conclusionsThe eukaryotic or bacterial "origin" of the RH50 gene remains unsolved. The RH50 prokaryotic HGT network suggests a preferential directionality of transfer from aerobic to anaerobic organisms. The observed HGT events between archaeal methanogens, anaerobic and aerobic ammonia-oxidizing bacteria suggest that syntrophic relationships play a major role in the structuring of the network, and point to oxygen minimum zones as an ecological niche that might be of crucial importance for HGT-driven evolution.
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