ArticleJournal of Korean medical science2017
Factors Associated with the Presence and Severity of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Korean Children and Adolescents.
Article in Journal of Korean medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 58 citations in OpenAlex.
- Hyperlactatemia associated with diabetic ketoacidosis in pediatric intensive care unit.BMC endocrine disorders · 2021Trial
- Time to Resolution of Diabetic Ketoacidosis and Its Predictors among Adult Diabetic Patients in Public Hospitals of Northeast, Ethiopia.Scientific reports · 2026Article
- Enhancing Primary Care Recognition of Type 1 Diabetes in Children: Diagnostic Challenges and Strategies to Prevent Diabetic Ketoacidosis.Journal of clinical medicine · 2026Review
- Determinants of diabetic ketoacidosis among adults with diabetes mellitus at the Ambo town Hospitals, Ethiopia.Scientific reports · 2025Article
- The impact of COVID-19 pandemic on the incidence, presentation, and management of type 1 diabetes in children and adolescents: a narrative review.Hormones (Athens, Greece) · 2025Review
- Recovery time of diabetic ketoacidosis in Africa: Systematic review and meta-analysis.Metabolism open · 2025Article
- Deciphering the role of lactate as a prognostic indicator in pediatric diabetic ketoacidosis.Wiener klinische Wochenschrift · 2025Article
- Factors associated with severe diabetic ketoacidosis in patients diagnosed with type 1 diabetes: a decade-long cross-sectional analysis.The Journal of international medical research · 2024Article
- Predictors of the clinical severity of T1DM presentation at diagnosis in children and adolescents with type 1 diabetes mellitus (T1DM).Hormones (Athens, Greece) · 2024Article
- Association between COVID-19 and the incidence of type 1 diabetes in Portugal - a registry study.BMC endocrine disorders · 2024Article
- Article
- SARS-CoV-2 Positive Serology and Islet Autoantibodies in Newly Diagnosed Pediatric Cases of Type 1 Diabetes Mellitus: A Single-Center Cohort Study.International journal of molecular sciences · 2023Observational
- The role of anion gap normalization time in the management of pediatric diabetic ketoacidosis.Frontiers in pediatrics · 2023Article
- The role of C-peptide in diabetes and its complications: an updated review.Frontiers in endocrinology · 2023Review
- Neutrophil-to-Lymphocyte Ratio Adds Valuable Information Regarding the Presence of DKA in Children with New-Onset T1DM.Journal of clinical medicine · 2022Article
- Comparison of Initial Presentation of Pediatric Diabetes Before and During the Coronavirus Disease 2019 Pandemic Era.Journal of Korean medical science · 2022Article
- Comparison of the clinical characteristics and outcomes of pediatric patients with and without diabetic ketoacidosis at the time of type 1 diabetes diagnosis.Annals of pediatric endocrinology & metabolism · 2022Article
- Risk Factors and Laboratory Findings Associated With Diabetic Ketoacidosis in Hospitalized Pediatric Patients.Cureus · 2022Article
- Diabetes ketoacidosis recovery in youth with newly diagnosed and established type 1 diabetes.Pediatric research · 2022Article
- Incidence of Type 1 diabetes and factors associated with presence and severity of ketoacidosis at onset in children.Acta bio-medica : Atenei Parmensis · 2022Article
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Authors and funding
12 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to identify the risk factors for presence and severity of diabetic ketoacidosis (DKA) at the onset of type 1 diabetes mellitus (T1DM) in Korean children and adolescents. A retrospective chart review of children and adolescents newly diagnosed with T1DM was conducted in seven secondary and tertiary centers in Korea. Eligible subjects were < 20 years of age and had records on the presence or absence of DKA at the time of T1DM diagnosis. DKA severity was categorized as mild, moderate, or severe. Data were collected on age, height, body weight, pubertal status, family history of diabetes, delayed diagnosis, preceding infections, health insurance status, and parental education level. A total of 361 patients (male 46.3%) with T1DM were included. Overall, 177 (49.0%) patients presented with DKA at T1DM diagnosis. Risk factors predicting DKA at T1DM diagnosis were age ≥ 12 years, lower serum C-peptide levels, presence of a preceding infection, and delayed diagnosis. Low parental education level and preceding infection increased the severity of DKA. These results suggest that alertness of the physician and public awareness of diabetes symptoms are needed to decrease the incidence and severity of DKA at T1DM diagnosis.
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