Observational studyCerebrovascular diseases (Basel, Switzerland)2017
Refining Prognosis for Intracerebral Hemorrhage by Early Reassessment.
Observational study in Cerebrovascular diseases (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Predicting long-term outcomes in acute intracerebral haemorrhage using delayed prognostication scores.Stroke and vascular neurology · 2021Trial
- Article
- Golden hour management in the patient with intraparenchymal cerebral hemorrhage: an Italian intersociety document.Journal of anesthesia, analgesia and critical care · 2025Review
- Blood Pressure Variability and Outcome Predictors for Traumatic Brain Injury Patients with Diffuse Axonal Injury: A Retrospective Cohort Study.The western journal of emergency medicine · 2025Article
- Recent Trends in the Withdrawal of Life-Sustaining Treatment in Patients with Acute Cerebrovascular Disease : 2017-2021.Journal of Korean Neurosurgical Society · 2024Article
- Prediction of poor outcome in stroke patients using radiomics analysis of intraparenchymal and intraventricular hemorrhage and clinical factors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Radiomics features from perihematomal edema for prediction of prognosis in the patients with basal ganglia hemorrhage.Frontiers in neurology · 2022Article
- Prognostication after intracerebral hemorrhage: a review.Neurological research and practice · 2021Review
- Epidemiological characteristics of 561 cases of intracerebral hemorrhage in Chengdu, China.Medicine · 2021Article
- The Feasibility and Validity of Objective and Patient-Reported Measurements of Cognition During Early Critical Illness Recovery.Neurocritical care · 2021Article
- End-of-Life Care Decision-Making in Stroke.Frontiers in neurology · 2021Review
- Scoping Review and Commentary on Prognostication for Patients with Intracerebral Hemorrhage with Advances in Surgical Techniques.Neurocritical care · 2020Article
- Early Stroke Recognition and Time-based Emergency Care Performance Metrics for Intracerebral Hemorrhage.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2020Observational
- Race, Socioeconomic Status, and Gastrostomy after Spontaneous Intracerebral Hemorrhage.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2020Observational
- Gap Analysis Regarding Prognostication in Neurocritical Care: A Joint Statement from the German Neurocritical Care Society and the Neurocritical Care Society.Neurocritical care · 2019Article
- Assessment and comparison of the max-ICH score and ICH score by external validation.Neurology · 2018Observational
- Impact of Recent Studies for the Treatment of Intracerebral Hemorrhage.Current neurology and neuroscience reports · 2018Review
- Update on the Treatment of Spontaneous Intraparenchymal Hemorrhage: Medical and Interventional Management.Current treatment options in neurology · 2018Review
- Predicting Prognosis of Intracerebral Hemorrhage (ICH): Performance of ICH Score Is Not Improved by Adding Oral Anticoagulant Use.Frontiers in neurology · 2018Article
- Intracerebral Hemorrhage with Intraventricular Extension-Getting the Prognosis Right Early.Frontiers in neurology · 2017Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundPrognostic assessments, which are crucial for decision-making in critical illnesses, have shown unsatisfactory reliability. We compared the accuracy of a widely used prognostic score against a model derived from clinical data obtained 5 days after admission for patients with intracerebral hemorrhage (ICH), a condition for which prognostication has proven notoriously challenging and prone to bias.
methodsPatients enrolled in a prospective observational cohort study of spontaneous ICH underwent hourly Glasgow Coma Scale (GCS) assessment. Outcome was measured at 3 months using the modified Rankin Scale (mRS). We analyzed the change in correlation between GCS and 3-month mRS scores from admission through day 5, and compared the performance of a parsimonious set of day 5 clinical variables against the ICH score.
resultsData was collected on 254 subjects. The ICH score and day 5 GCS score were both correlated with 3-month mRS score (p < 0.001), but the correlation was stronger with day 5 GCS score (p < 0.05 by Fisher z-transformation). Premorbid mRS score, intraventricular hemorrhage and day 5 GCS score were independent predictors of outcome (all p < 0.05 in ordinal regression model). While ICH score correctly classified good (mRS 0-3) vs. poor (mRS 4-6) outcome in 73% of cases, the day 5 model correctly classified 83% of cases.
conclusionsA simple reassessment after 5 days of care significantly improves the accuracy of prognosticating outcome in patients with ICH. These data confirm the feasibility and potential utility of early reassessments in refining prognosis for patients who survive early stabilization of a severe neurologic injury.
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