SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2017
Association between morning symptoms and physical activity in COPD: a systematic review.
Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Daytime symptoms of chronic obstructive pulmonary disease: a systematic review.NPJ primary care respiratory medicine · 2020Pooled it
- Trial
- High 24-Hour Respiratory Symptoms and Low Physical Activity in the Stable COPD Romanian Cohort of SPACE Study.International journal of chronic obstructive pulmonary diseaseTrial
- Integrative multi-omics and machine learning identify CHRNA1 putative circadian-immune hub in COPD.PloS one · 2026Article
- Screening COPD-Related Biomarkers and Traditional Chinese Medicine Prediction Based on Bioinformatics and Machine Learning.International journal of chronic obstructive pulmonary disease · 2024Article
- COPD - do the right thing.BMC family practice · 2021Review
- Chronic Obstructive Pulmonary Disease: Epidemiology, Biomarkers, and Paving the Way to Lung Cancer.Journal of clinical medicine · 2021Review
- Are in Person and Telephone Interviews Equivalent Modes of Administrating the CAT, the FACIT-FS and the SGRQ in People With COPD?Frontiers in rehabilitation sciences · 2021Article
- The Exercising Brain: An Overlooked Factor Limiting the Tolerance to Physical Exertion in Major Cardiorespiratory Diseases?Frontiers in human neuroscience · 2021Review
- Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease: Highly Effective but Often Overlooked.Tuberculosis and respiratory diseases · 2020Article
- Importance of the relationship between symptoms and self-reported physical activity level in stable COPD based on the results from the SPACE study.Respiratory research · 2019Observational
- Impact of symptom variability on clinical outcomes in COPD: analysis of a longitudinal cohort.International journal of chronic obstructive pulmonary disease · 2019Article
- Locomotor Muscles in COPD: The Rationale for Rehabilitative Exercise Training.Frontiers in physiology · 2019Review
- Physical activity in the morning and afternoon is lower in patients with chronic obstructive pulmonary disease with morning symptoms.Respiratory research · 2018Observational
- The impacts of morning, daytime, and nighttime symptoms on disease burden in real-world patients with COPD.International journal of chronic obstructive pulmonary disease · 2018Article
- Daily Objective Physical Activity and Sedentary Time in Adults with COPD Using Spirometry Data from Canadian Measures Health Survey.Canadian respiratory journal · 2018Article
- Does pulmonary rehabilitation alleviate depression in older patients with chronic obstructive pulmonary disease.Saudi medical journal · 2017Article
- Understanding the impact of symptoms on the burden of COPD.Respiratory research · 2017Review
- The association between objectively measured physical activity and morning symptoms in COPD.International journal of chronic obstructive pulmonary disease · 2017Observational
- Diurnal and seasonal variation in six-minute walk distance in pulmonary hypertension: Implications for clinical monitoring.Chronic respiratory diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Morning symptoms are common in chronic obstructive pulmonary disease (COPD). Many COPD patients consider the morning as the most troublesome part of the day, in which they experience more symptoms and physical activity limitations.To systematically report evidence of the association between morning symptoms and physical activity in COPD patients, a literature search was conducted using relevant MESH terms and text words in PubMed, Embase, Web of Science, COCHRANE, CINAHL and PsycINFO. Quality of the articles was assessed with validated checklists.Eight studies were included. Morning symptoms were present in 39.8-94.4%. In 37.0-90.6% of all COPD patients, there was an association between physical activity and morning symptoms. However, causality could not be proved. Morning symptoms were associated with a sedentary lifestyle (p<0.05). Treatment in line with the guidelines improved the degree of activity limitations due to morning symptoms (p<0.0001).Across all disease stages, COPD patients experience morning symptoms which are negatively associated with physical activity. Physicians should consider morning symptoms as a treatment goal. Pharmacotherapy may improve the degree of activity limitations due to morning symptoms. More objective research should focus on symptoms, activity limitations and physical inactivity of COPD patients, especially in the morning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.