Evidence map›Paper›PMID 28049029›Full record

ArticleNeuroscience2017

Glutamate transporter type 3 participates in maintaining morphine-induced conditioned place preference.

Li Wan, Jiangjiang Bi, Jun Li, Zhiyi Zuo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. New Approaches to Addiction Treatment Based on Learning and Memory.Current topics in behavioral neurosciences · 2025
    Review
  2. Glutamatergic Systems and Memory Mechanisms Underlying Opioid Addiction.Cold Spring Harbor perspectives in medicine · 2021
    Review
  3. Review
  4. Article
  5. Glutamate Transport: A New Bench to Bedside Mechanism for Treating Drug Abuse.The international journal of neuropsychopharmacology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Li WanDepartment of Anesthesiology, University of Virginia, Charlottesville, VA, United States; Department of Anesthesiology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Jiangjiang BiDepartment of Anesthesiology, University of Virginia, Charlottesville, VA, United States; Department of Anesthesiology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Jun LiDepartment of Anesthesiology, University of Virginia, Charlottesville, VA, United States.
Zhiyi ZuoDepartment of Anesthesiology, University of Virginia, Charlottesville, VA, United States. Electronic address: zz3c@virginia.edu.
University of Virginia · USHuazhong University of Science and Technology · CN

Funding

Volatile anesthetic modulation of glutamate transportersR01GM065211 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI ZUO, ZHIYI · 2003 to 2011
$2.6M
Volatile anesthetic effects on aging brainR01GM098308 · NIGMS · UNIVERSITY OF VIRGINIA · PI ZUO, ZHIYI · 2012 to 2015
$1.2M
NIGMS NIH HHS R01 GM065211NIGMS NIH HHS R01 GM098308
6 · The paper itself

Abstract

Glutamate transporters (EAAT) have been implicated in the drug addiction behavior. We determined whether EAAT type 3 (EAAT3) played a role in morphine addiction. Six- to eight-week-old EAAT3 knockout (EAAT3

Indexed as

AnimalsBlotting, WesternBrainConditioning, PsychologicalExcitatory Amino Acid AntagonistsExcitatory Amino Acid Transporter 3Extinction, PsychologicalFemaleMaleMice, KnockoutMorphineMorphine DependenceNarcoticsRiluzoleSpatial BehaviorExcitatory Amino Acid AntagonistsExcitatory Amino Acid Transporter 3MorphineNarcoticsRiluzoleSlc1a1 protein, mouseconditioned place preferenceglutamate transportermicemorphine

Identifiers

PMID28049029
PMCPMC5303644
OpenAlexW2566580855

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.