SynthesisPloS one2017
Cavity Shaving plus Lumpectomy versus Lumpectomy Alone for Patients with Breast Cancer Undergoing Breast-Conserving Surgery: A Systematic Review and Meta-Analysis.
Synthesis in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Does cavity margin shaving reduce residual tumor and re-excision rates? A systematic review.Archives of gynecology and obstetrics · 2023Pooled it
- No cancer left behind: a testbed and demonstration of concept for photoacoustic tumor bed inspection.Computer assisted surgery (Abingdon, England) · 2026Article
- Margin Assessment in Breast-Conserving Surgery: A Comparative Analysis of Frozen Section and Cavity Shave Techniques.Annals of surgical oncology · 2026Article
- Article
- Margin Matters: Advances in Intraoperative Margin Assessment for Breast-Conserving Surgery.Diagnostics (Basel, Switzerland) · 2025Review
- Digital morphometry illustrates a relationship between percentage of ductal carcinoma in-situ in breast needle core biopsy and margin status at lumpectomy.Journal of pathology informatics · 2025Article
- Article
- Cost minimization in breast conserving surgery: a comparative study of radiofrequency spectroscopy and full cavity shave margins.Cost effectiveness and resource allocation : C/E · 2023Article
- Impact of cavity shaving on residual tumor rates in patients with primary invasive carcinoma and carcinoma in situ in breast conserving surgery.Archives of gynecology and obstetrics · 2023Article
- Routine four-quadrant cavity shaving at the time of wide local excision for breast cancer reduces re-excision rate.Annals of the Royal College of Surgeons of England · 2023Article
- Development of intraoperative assessment of margins in breast conserving surgery: a narrative review.Gland surgery · 2022Review
- Letter to the Editor: The Impact of Neoadjuvant Chemotherapy on Margin Re-excision in Breast-Conserving Surgery.World journal of surgery · 2022Article
- Developing diagnostic assessment of breast lumpectomy tissues using radiomic and optical signatures.Scientific reports · 2021Article
- Radiological Underestimation of Tumor Size Influences the Success Rate of Re-Excision after Breast-conserving Surgery.European journal of breast health · 2021Article
- Margin Assessment and Re-excision Rates for Patients Who Have Neoadjuvant Chemotherapy and Breast-Conserving Surgery.Annals of surgical oncology · 2021Article
- Performance of a novel protease-activated fluorescent imaging system for intraoperative detection of residual breast cancer during breast conserving surgery.Breast cancer research and treatment · 2021Article
- The Value of Repeated Breast Surgery as a Quality Indicator in Breast Cancer Care.Annals of surgical oncology · 2021Article
- Reoperation rate after breast conserving surgery as quality indicator in breast cancer treatment: A reappraisal.Breast (Edinburgh, Scotland) · 2020Article
- Imaging in Locoregional Management of Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2020Review
- A tale of two operations: re-excision as a quality measure.Gland surgery · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The margin status is a well-established prognostic predictor for patients undergoing breast-conserving surgery (BCS). Recent data suggested that cavity shaving in addition to lumpectomy might be a promising approach for improving the clinical outcomes. We aimed to compare the efficacy and safety between cavity shaving plus lumpectomy and lumpectomy alone with a systematic review and meta-analysis. We searched the PubMed, Embase, and Cochrane CENTRAL databases for studies comparing cavity shaving with lumpectomy before June 10, 2016. Both comparative studies and self-control studies were included. A random-effects model was used to estimate the odds ratios (ORs) for positive margin rate, reoperation rate, recurrence rate, and weighted mean difference (WMD) for excised tissue volume. Twenty-six studies were included in the meta-analysis. The cavity shaving group had a significantly lower positive margin rate than the BCS-alone group (16.4% vs. 31.9%; OR = 0.41, 95% CI 0.32-0.53, P < 0.05). Cavity shaving was associated with a significantly decreased rate of reoperation (OR = 0.42, 95% CI 0.30-0.59, P < 0.05). The overall locoregional rate was low for cavity shaving and BCS-alone (3% vs. 4%). Cavity shaving had no significant effect on the risk of locoregional recurrence (OR = 0.86, 95% CI 0.32-2.35; P = 0.78). The excised tissue volume did not differ substantially between cavity shaving and BCS alone (WMD = -23.88, 95% CI -55.20 to 7.44, P = 0.14). For patients undergoing BCS, additional cavity shaving was an effective method to decrease the positive margin rate and avoid reoperation. The addition of cavity shaving did not appear to have excessive excised tissue volume compared with partial mastectomy alone.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.