Evidence map›Paper›PMID 28046049›Full record

SynthesisPloS one2017

Health Care Needs and Support for Patients Undergoing Treatment for Prosthetic Joint Infection following Hip or Knee Arthroplasty: A Systematic Review.

Setor K Kunutsor, Andrew D Beswick, Tim J Peters, Rachael Gooberman-Hill, Michael R Whitehouse, Ashley W Blom, Andrew J Moore

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04858217 (Diagnostic Accuracy and Cost-effectiveness Analysis of Serum and Synovial Fluid Markers for the Diagnosis of Periprosthetic Hip and Knee Joint Infections), which is not on this map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04858217 recruitingnot on this mapstarted 2022, after this paper: background citation

Diagnostic Accuracy and Cost-effectiveness Analysis of Serum and Synovial Fluid Markers for the Diagnosis of Periprosthetic Hip and Knee Joint Infections

TypeobservationalSponsorIstituto Ortopedico RizzoliRan2022 to 2026Enrolled270ConditionsProsthetic Joint Infection
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  4. Local antibiotics in primary hip and knee arthroplasty: a systematic review and meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Setor K KunutsorMusculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
Andrew D BeswickMusculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
Tim J PetersMusculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
Rachael Gooberman-HillMusculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
Michael R WhitehouseMusculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
Ashley W BlomMusculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
Andrew J MooreMusculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.ORCID http://orcid.org/0000-0003-3185-1599
University of Bristol · GB

Funding

Department of Health RP-PG-1210-12005
6 · The paper itself

Abstract

backgroundHip and knee arthroplasty are common interventions for the treatment of joint conditions, most notably osteoarthritis. Although many patients benefit from surgery, approximately 1% of patients develop infection afterwards known as deep prosthetic joint infection (PJI), which often requires further major surgery.

objectiveTo assess support needs of patients undergoing treatment for PJI following hip or knee arthroplasty and to identify and evaluate what interventions are routinely offered to support such patients.

designSystematic review. DATA SOURCES: MEDLINE, EMBASE, Web of Science, PsycINFO, Cinahl, Social Science Citation Index, The Cochrane Library, and reference lists of relevant studies from January 01, 1980 to October 05, 2016. SELECTION CRITERIA: Observational (prospective or retrospective cohort, nested case-control or case-control) studies, qualitative studies, or clinical trials conducted in patients treated for PJI and/or other major adverse occurrences following hip or knee arthroplasty. REVIEW

methodsData were extracted by two independent investigators and consensus was reached with involvement of a third. Given the heterogeneous nature of study designs, methods, and limited number of studies, a narrative synthesis is presented.

resultsOf 4,213 potentially relevant citations, we identified one case-control, one prospective cohort and two qualitative studies for inclusion in the synthesis. Patients report that PJI and treatment had a profoundly negative impact affecting physical, emotional, social and economic aspects of their lives. No study evaluated support interventions.

conclusionThe findings demonstrate that patients undergoing treatment for PJI have extensive physical, psychological, social and economic support needs. The interpretation of study results is limited by variation in study design, outcome measures and the small number of relevant eligible studies. However, our review highlights a lack of evidence about support strategies for patients undergoing treatment for PJI and other adverse occurrences following hip or knee arthroplasty. There is a need to design, implement and evaluate interventions to support these patients. SYSTEMATIC REVIEW REGISTRATION: PROSPERO 2015: CRD42015027175.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeDelivery of Health CareHumansJoint DiseasesOsteoarthritisPostoperative ComplicationsProsthesis-Related InfectionsSocial SupportTreatment Outcome

Identifiers

PMID28046049
PMCPMC5207523
OpenAlexW2567839601

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.