ArticleThe ISME journal2017
Redox potential as a master variable controlling pathways of metal reduction by Geobacter sulfurreducens.
Article in The ISME journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed.
- Overview of pathways and dynamic interactions of c-type cytochromes in Geobacter sulfurreducens.Biochemical Society transactions · 2026Review
- Improving the Biocompatibility and Energy Performance of a Microbial Bioanode with Black Phosphorus and Polypyrrole Nanocomposites.ACS omega · 2026Article
- Environmental considerations and bioremediation applications of the metal-, nitrate-, and organohalide-respiring bacteriumApplied and environmental microbiology · 2026Review
- Propionate oxidation byApplied and environmental microbiology · 2026Article
- Cross-scale design of abiotic-biotic interfaces for semi-artificial photosynthesis.Chemical science · 2026Review
- Novel energy utilization mechanisms of microorganisms in the hydrosphere.Fundamental research · 2025Review
- Influence of support materials on the electroactive behavior, structure and gene expression of wild type and GSU1771-deficient mutant of Geobacter sulfurreducens biofilms.Environmental science and pollution research international · 2025Article
- Extracellular electron transfer proteins contribute to reduction of ferric minerals byApplied and environmental microbiology · 2025Article
- Cometabolism of ferrihydrite reduction and methyl-dismutating methanogenesis byApplied and environmental microbiology · 2025Article
- Duration of OEnvironmental science & technology · 2025Article
- Independently evolved extracellular electron transfer pathways in ecologically diverse Desulfobacterota.The ISME journal · 2025Article
- Electron transport across the cell envelope via multihemeFrontiers in chemistry · 2025Review
- Microbial and chemical predictors of methane release from a stratified thermokarst permafrost hotspot.Frontiers in microbiology · 2025Article
- A survey of the Desulfuromonadia "cytochromome" provides a glimpse of the unexplored diversity of multiheme cytochromes in nature.BMC genomics · 2024Article
- Isolation and genomic analysis of "Applied and environmental microbiology · 2024Article
- Article
- Characterization of the inner membrane cytochrome ImcH from Geobacter reveals its importance for extracellular electron transfer and energy conservation.Protein science : a publication of the Protein Society · 2023Article
- Metabolically diverse microorganisms mediate methylmercury formation under nitrate-reducing conditions in a dynamic hydroelectric reservoir.The ISME journal · 2023Article
- Multi-heme cytochrome-mediated extracellular electron transfer by the anaerobic methanotroph 'Candidatus Methanoperedens nitroreducens'.Nature communications · 2023Article
- Nitrogen Fixation and Ammonium Assimilation Pathway Expression of Geobacter sulfurreducens Changes in Response to the Anode Potential in Microbial Electrochemical Cells.Applied and environmental microbiology · 2023Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Geobacter sulfurreducens uses at least two different pathways to transport electrons out of the inner membrane quinone pool before reducing acceptors beyond the outer membrane. When growing on electrodes poised at oxidizing potentials, the CbcL-dependent pathway operates at or below redox potentials of -0.10 V vs the standard hydrogen electrode, whereas the ImcH-dependent pathway operates only above this value. Here, we provide evidence that G. sulfurreducens also requires different electron transfer proteins for reduction of a wide range of Fe(III)- and Mn(IV)-(oxyhydr)oxides, and must transition from a high- to low-potential pathway during reduction of commonly studied soluble and insoluble metal electron acceptors. Freshly precipitated Fe(III)-(oxyhydr)oxides could not be reduced by mutants lacking the high-potential pathway. Aging these minerals by autoclaving did not change their powder X-ray diffraction pattern, but restored reduction by mutants lacking the high-potential pathway. Mutants lacking the low-potential, CbcL-dependent pathway had higher growth yields with both soluble and insoluble Fe(III). Together, these data suggest that the ImcH-dependent pathway exists to harvest additional energy when conditions permit, and CbcL switches on to allow respiration closer to thermodynamic equilibrium conditions. With evidence of multiple pathways within a single organism, the study of extracellular respiration should consider not only the crystal structure or solubility of a mineral electron acceptor, but rather the redox potential, as this variable determines the energetic reward affecting reduction rates, extents, and final microbial growth yields in the environment.
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