Evidence map›Paper›PMID 28045446›Full record

ReviewMolecules (Basel, Switzerland)2017

Biological Activities of Essential Oils: From Plant Chemoecology to Traditional Healing Systems.

Javad Sharifi-Rad, Antoni Sureda, Gian Carlo Tenore, Maria Daglia, Mehdi Sharifi-Rad, Marco Valussi, Rosa Tundis, Marzieh Sharifi-Rad, Monica R Loizzo, Adedayo Oluwaseun Ademiluyi and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 293 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
293citing papers in PubMed, 5 pooled it
63.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

293 citing papers in PubMed, 5 syntheses or guidelines pooled it, 821 citations in OpenAlex.

  1. Pooled it
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  5. The Use ofCannabis and cannabinoid research · 2022
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  13. Chemical Characterization and Bioactive Potential ofMolecules (Basel, Switzerland) · 2026
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  15. Unveiling the Pharmacological Potential ofInternational journal of molecular sciences · 2026
    Article
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233 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 5 countries.

Javad Sharifi-RadPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, 981991953381 Tehran, Iran. javad.sharifirad@gmail.com.
Antoni SuredaResearch Group on Community Nutrition and Oxidative Stress, University of Balearic Islands, E-07122 Palma de Mallorca, Spain. tosugo@hotmail.com.
Gian Carlo TenoreDepartment of Pharmacy, University of Naples "Federico II", Via Domenico Montesano, 80131 Napoli, Italy. giancarlo.tenore@unina.it.
Maria DagliaDepartment of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, Pavia University, Viale Taramelli 12, 27100 Pavia, Italy. maria.daglia@unipv.it.
Mehdi Sharifi-RadDepartment of Medical Parasitology, Zabol University of Medical Sciences, 61663335 Zabol, Iran. mehdi_sharifirad@yahoo.com.
Marco ValussiEuropean Herbal and Traditional Medicine Practitioners Association (EHTPA), 25 Lincoln Close, GL20 5TY Tewkesbury, UK. marco.officinalessinia@gmail.com.
Rosa TundisDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy. rosa.tundis@unical.it.
Marzieh Sharifi-RadDepartment of Chemistry, Faculty of Science, University of Zabol, 98615-538 Zabol, Iran. marzieh.sharifirad@gmail.com.
Monica R LoizzoDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy. mr.loizzo@unical.it.
Adedayo Oluwaseun AdemiluyiFunctional Foods, Nutraceuticals and Phytomedicine Unit, Department of Biochemistry, Federal University of Technology, 340001 Akure, Nigeria. ademiluyidayo@yahoo.co.uk.
Razieh Sharifi-RadPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, 981991953381 Tehran, Iran. razieh.sharifirad@gmail.com.
Seyed Abdulmajid AyatollahiPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, 981991953381 Tehran, Iran. tosugo@hotmail.com.
Marcello IritiDepartment of Agricultural and Environmental Sciences, Milan State University, via G. Celoria 2, 20133 Milan, Italy. marcello.iriti@unimi.it.
Shahid Beheshti University of Medical Sciences · IRUniversity of Calabria · ITZabol University · IRFederal University of Technology · NGFederico II University Hospital · ITInstituto de Salud Carlos III · ESUniversity of Milan · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Essential oils are complex mixtures of hydrocarbons and their oxygenated derivatives arising from two different isoprenoid pathways. Essential oils are produced by glandular trichomes and other secretory structures, specialized secretory tissues mainly diffused onto the surface of plant organs, particularly flowers and leaves, thus exerting a pivotal ecological role in plant. In addition, essential oils have been used, since ancient times, in many different traditional healing systems all over the world, because of their biological activities. Many preclinical studies have documented antimicrobial, antioxidant, anti-inflammatory and anticancer activities of essential oils in a number of cell and animal models, also elucidating their mechanism of action and pharmacological targets, though the paucity of in human studies limits the potential of essential oils as effective and safe phytotherapeutic agents. More well-designed clinical trials are needed in order to ascertain the real efficacy and safety of these plant products.

Indexed as

Anti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsFlowersHumansOils, VolatilePlant OilsWound HealingAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsOils, VolatilePlant Oilsantimicrobial activityethnobotanyisoprenoidsmonoterpenesoral healthcaretraditional healing systems

Identifiers

PMID28045446
PMCPMC6155610
OpenAlexW2562282801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.