Evidence map›Paper›PMID 28045438›Full record

ArticlePharmaceuticals (Basel, Switzerland)2017

D11-Mediated Inhibition of Protein Kinase CK2 Impairs HIF-1α-Mediated Signaling in Human Glioblastoma Cells.

Susanne Schaefer, Tina H Svenstrup, Mette Fischer, Barbara Guerra

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Susanne SchaeferDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, 5230 Odense, Denmark. sschaefer@bmb.sdu.dk.
Tina H SvenstrupDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, 5230 Odense, Denmark. thl@bmb.sdu.dk.
Mette FischerDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, 5230 Odense, Denmark. mettefischer@outlook.com.
Barbara GuerraDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, 5230 Odense, Denmark. bag@bmb.sdu.dk.
University of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Compelling evidence indicates that protein kinase CK2 plays an important role in many steps of cancer initiation and progression, therefore, the development of effective and cell-permeable inhibitors targeting this kinase has become an important objective for the treatment of a variety of cancer types including glioblastoma. We have recently identified 1,3-dichloro-6-[(

Indexed as

CK2D11gene expression profilingglioblastoma cellsHIF-1α

Identifiers

PMID28045438
PMCPMC5374409
OpenAlexW2562661635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.