ArticlePsychiatric services (Washington, D.C.)2017
First Presentation With Psychotic Symptoms in a Population-Based Sample.
Article in Psychiatric services (Washington, D.C.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Systematic Review and Meta-Analysis: Risk Factors of Violence During First-Episode Psychosis.Trauma, violence & abuse · 2026Pooled it
- Digital Health Interventions for Informal Family Caregivers of People With First-Episode Psychosis: Systematic Review on User Experience and Effectiveness.JMIR mental health · 2024Pooled it
- Systematic Review and Meta-analysis: Rates of Violence During First-Episode Psychosis (FEP).Schizophrenia bulletin · 2024Pooled it
- International incidence of psychotic disorders, 2002-17: a systematic review and meta-analysis.The Lancet. Public health · 2019Pooled it
- Cognitive Training and Remediation in First-Episode Psychosis: A Literature Review.Journal of the American Psychiatric Nurses AssociationPooled it
- Effects of Online Acceptance and Commitment Therapy for Family Members of Individuals With Early Psychosis on Self-Stigma, Coping Strategies and Resilience: A Randomized Controlled Trial.Journal of psychiatric and mental health nursing · 2026Trial
- Examining the Effectiveness of a Digital Media Campaign at Reducing the Duration of Untreated Psychosis in New York State: Results From a Stepped-wedge Randomized Controlled Trial.Schizophrenia bulletin · 2024Trial
- Racial-Ethnic Disparities in First-Episode Psychosis Treatment Outcomes From the RAISE-ETP Study.Psychiatric services (Washington, D.C.) · 2018Trial
- Understanding Community-Level Determinants and Navigating Care for Psychosis: The Experiences of Black Service Users and Their Family Members.Journal of racial and ethnic health disparities · 2026Article
- The Risk of Very Late-Onset Schizophrenia Following Diabetes Type 2 Onset: A Nationwide Population-Based Study of Midlife and Old-Age.Schizophrenia bulletin · 2026Article
- Article
- Plasma microRNA signatures in drug-naïve Romanian adolescents with first-episode psychosis.Frontiers in psychiatry · 2026Article
- Cognitive Behavioral Therapy in Early Intervention for Psychosis: A Cost-Effectiveness Analysis.Journal of health economics and outcomes research · 2026Article
- Connection Learning Healthcare System Hub of the Early Psychosis Intervention Network: Program and Participant Characteristics.Early intervention in psychiatry · 2025Article
- Identifying Barriers and Pathways to Care Among College Students at Risk of or Diagnosed with First Episode Psychosis.Psychiatry international · 2025Article
- Building a two-state learning healthcare system for persons with first episode psychosis.Schizophrenia research · 2025Article
- Developing an algorithm to identify individuals with psychosis in secondary care in England: application using the Mental Health Services Data Set.BJPsych open · 2025Article
- Validation of an ICD-Code-Based Case Definition for Psychotic Illness Across Three Health Systems.Schizophrenia bulletin · 2024Article
- Length of hospital stay in involuntary admissions in Greece: a 10-year retrospective observational study.Social psychiatry and psychiatric epidemiology · 2024Observational
- Clozapine Use Among People With Psychotic Disorders Who Experience Specific Indications for Clozapine.The Journal of clinical psychiatry · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectiveIncreasing evidence supports the effectiveness of comprehensive early intervention at first onset of psychotic symptoms. Implementation of early intervention programs will require population-based data on overall incidence of psychotic symptoms and on care settings of first presentation.
methodsIn five large health care systems, electronic health records data were used to identify all first occurrences of psychosis diagnoses among persons ages 15-59 between January 1, 2007, and December 31, 2013 (N=37,843). For a random sample of these putative cases (N=1,337), review of full-text medical records confirmed clinician documentation of psychotic symptoms and excluded those with documented prior diagnosis of or treatment for psychosis. Initial incidence rates (based on putative cases) and confirmation rates (from record reviews) were used to estimate true incidence according to age and setting of initial presentation.
resultsAnnual incidence estimates based on putative cases were 126 per 100,000 among those ages 15-29 and 107 per 100,000 among those ages 30-59. Rates of chart review confirmation ranged from 84% among those ages 15-29 diagnosed in emergency department or inpatient mental health settings to 19% among those ages 30-59 diagnosed in general medical outpatient settings. Estimated true incidence rates were 86 per 100,000 per year among those ages 15-29 and 46 per 100,000 among those ages 30-59.
conclusionsWhen all care settings were included, incidence of first-onset psychotic symptoms was higher than previous estimates based on surveys or inpatient data. Early intervention programs must accommodate frequent presentation after age 30 and presentation in outpatient settings, including primary care.
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