ArticleHuman brain mapping2017
Impact of correction factors in human brain lesion-behavior inference.
Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.
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Who cites it
74 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A meta-analysis of functional neuroimaging tasks associated with pseudoneglect.Experimental brain research · 2025Pooled it
- Neuroanatomical correlates of stroke-related dizziness and vertigo: secondary analysis from the INSPiRE-TMS trial.Journal of neurology · 2026Trial
- The Influence of Contralesional Brain Age Gradients on Chronic Stroke Aphasia Severity and Treatment Response.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Critical-Network Lesion-Symptom Mapping.Human brain mapping · 2026Article
- Methodological Choices Strongly Modulate the Sensitivity and Specificity of Lesion-Symptom Mapping Analyses.Human brain mapping · 2026Article
- Covert Embolic Brain Infarcts, Remote Cortical Thinning, and Cognitive Impairment in Atrial Fibrillation: An Analysis of the Swiss-AF Cohort.Cerebrovascular diseases (Basel, Switzerland) · 2026Article
- Article
- Network Localization of Fatigue in Multiple Sclerosis.Annals of clinical and translational neurology · 2026Article
- Post-stroke motivational decline was associated with lesions in the left deep white matter involving the corticospinal tract and superior longitudinal fasciculus.Brain imaging and behavior · 2026Article
- Cross-species lesion mapping links a midbrain circuit to vergence dysfunction.Brain : a journal of neurology · 2026Article
- Article
- Lesion locations associated with gait independence in patients with stroke: a support vector regression lesion-symptom mapping study.Neuroradiology · 2025Article
- Predictors and Implications of Myocardial Injury in Intracerebral Hemorrhage.Clinical neuroradiology · 2025Article
- Relationship between post-stroke trunk function and brain lesion locations: A support vector regression lesion-symptom mapping study.Journal of rehabilitation medicine · 2025Article
- Neuropsychiatric changes following striatal stroke- results from the observational PostPsyDis study.Neurological research and practice · 2025Article
- Visual feature processing in a large stroke cohort: evidence against modular organization.Brain : a journal of neurology · 2025Article
- Pathological features of post-stroke pain: a comprehensive analysis for subtypes.Brain communications · 2025Article
- From acute neglect to chronic constructional deficits: parietotemporal contributions to long-term post-stroke impairments.Brain communications · 2025Article
- FAT1-weighted MRI-guided focused ultrasound thalamotomy for essential tremor.BMJ neurology open · 2025Article
- The Aphasia Recovery Cohort, an open-source chronic stroke repository.Scientific data · 2024Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Statistical voxel-based lesion-behavior mapping (VLBM) in neurological patients with brain lesions is frequently used to examine the relationship between structure and function of the healthy human brain. Only recently, two simulation studies noted reduced anatomical validity of this method, observing the results of VLBM to be systematically misplaced by about 16 mm. However, both simulation studies differed from VLBM analyses of real data in that they lacked the proper use of two correction factors: lesion size and "sufficient lesion affection." In simulation experiments on a sample of 274 real stroke patients, we found that the use of these two correction factors reduced misplacement markedly compared to uncorrected VLBM. Apparently, the misplacement is due to physiological effects of brain lesion anatomy. Voxel-wise topographies of collateral damage in the real data were generated and used to compute a metric for the inter-voxel relation of brain damage. "Anatomical bias" vectors that were solely calculated from these inter-voxel relations in the patients' real anatomical data, successfully predicted the VLBM misplacement. The latter has the potential to help in the development of new VLBM methods that provide even higher anatomical validity than currently available by the proper use of correction factors. Hum Brain Mapp 38:1692-1701, 2017. © 2017 Wiley Periodicals, Inc.
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