ArticleInternational ophthalmology2018
Effects of age and gender on macular thickness in healthy subjects using spectral optical coherence tomography/scanning laser ophthalmoscopy.
Article in International ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Normative data for optical coherence tomography in children: a systematic review.Eye (London, England) · 2021Pooled it
- Influence of Refraction on Widefield Retinal and Choroidal Vascular Metrics in Optical Coherence Tomography Angiography in a Caucasian Population.Translational vision science & technology · 2026Article
- When Sex Matters: Differences in the Central Nervous System as Imaged by OCT through the Retina.Journal of imaging · 2023Article
- Sex-related difference in the retinal structure of young adults: a machine learning approach.Frontiers in medicine · 2023Article
- Mapping the thickness of retinal layers using Spectralis spectral domain optical coherence tomography in Indian eyes.Indian journal of ophthalmology · 2022Article
- Assessing reproducibility and the effects of demographic variables on the normal macular layers using the Spectralis SD-OCT.Clinical ophthalmology (Auckland, N.Z.) · 2018Article
- Retinal and Choroidal Thickness in an Indigenous Population from Ghana: Comparison with Individuals with European or African Ancestry.Ophthalmology scienceArticle
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo examine healthy subjects for normal macular thickness values and determine the effects of gender and age in a Turkish population, using spectral optical coherence tomography/scanning laser ophthalmoscopy (OCT/SLO). MATERIAL AND
methodSix hundred fourteen eyes of 307 subjects with no history of ocular diseases and normal ophthalmic examination were recruited in this cross-sectional, prospective study. The participants were divided into three groups based on age (between 20 and 29 years: group 1, between 30 and 39 years: group 2, between 40 and 49 years: group 3). All subjects were scanned with spectral OCT/SLO, performed by one examiner to acquire the retinal thickness map in the ETDRS grid, and values were recorded for nine sectors, and effects of age and gender were evaluated.
resultsWhen all the subjects were evaluated, the thicknesses were lower in women than men in all sectors (p < 0.001). When divided in groups based on age, this difference remained only in the outer segments. However, the differences in outer layers, except outer nasal layer, were thicker in women in group 3 when compared to others in group 3. When compared between groups, only central thickness in group 3 was shown to be higher than group 1 (p = 0.06). There was no significant difference of thicknesses in any sector when compared right and left eyes of all subjects.
conclusionsThe study reports the variation in retinal thickness between age and gender in a relatively large sample of a Turkish population. It is important to consider these effects while interpreting the OCT images to make an appropriate diagnosis in retinal diseases.
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