ArticleJournal of experimental botany2017
The OsHAPL1-DTH8-Hd1 complex functions as the transcription regulator to repress heading date in rice.
Article in Journal of experimental botany, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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31 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Meta-QTL and ortho-MQTL analyses identified genomic regions controlling rice yield, yield-related traits and root architecture under water deficit conditions.Scientific reports · 2021Pooled it
- The DTH8-SD1 pair regulates panicle architecture in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- 3D epigenome architecture orchestrates cis and trans regulation of flowering time in rice.Genome biology · 2026Article
- Characterization of resistance to bacterial panicle blight in rice revealed by transcriptome and QTL mapping analyses.Frontiers in plant science · 2026Article
- Rice OsFKF1 Promotes Degradation of OsPRR37 for Short-Day Early Flowering.Rice (New York, N.Y.) · 2025Article
- A multi-layered regulatory model uncovers the central role of OsPRR37 in coordinating multiple agronomic traits.BMC plant biology · 2025Article
- TaDL interacts with TaB3 and TaNF-YB1 to synergistically regulate the starch synthesis and grain quality in bread wheat.Journal of integrative plant biology · 2025Article
- A Series of Novel Alleles ofPlants (Basel, Switzerland) · 2025Article
- Functional divergence of FTL9 and FTL10 in flowering control in rice.BMC genomics · 2024Article
- Circadian and photoperiodic regulation of the vegetative to reproductive transition in plants.Communications biology · 2024Review
- Exploring the Effect of High-Energy Heavy Ion Beam on Rice Genome: Transposon Activation.Genes · 2023Article
- The WD40 domain-containing protein Ehd5 positively regulates flowering in rice (Oryza sativa).The Plant cell · 2023Article
- Molecular Links between Flowering and Abiotic Stress Response: A Focus onPlants (Basel, Switzerland) · 2023Review
- Rice functional genomics: decades' efforts and roads ahead.Science China. Life sciences · 2022Review
- The genetic mechanism of heterosis utilization in maize improvement.Genome biology · 2021Article
- Forecasting rice latitude adaptation through a daylength-sensing-based environment adaptation simulator.Nature food · 2021Article
- Transcriptional and post-transcriptional regulation of heading date in rice.The New phytologist · 2021Review
- OsRE1 interacts with OsRIP1 to regulate rice heading date by finely modulating Ehd1 expression.Plant biotechnology journal · 2021Article
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Authors and funding
19 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Heading date is an important agronomic trait related to crop yield. Many genes related to heading date have already been identified in rice (Oryza sativa), and a complicated, preliminary regulatory genetic network has also already been established, but the protein regulatory network is poorly understood. We have identified a novel heading date regulator, Heme Activator Protein like 1 (OsHAPL1), which inhibits flowering under long-day conditions. OsHAPL1 is a nuclear-localized protein that is highly expressed in leaves in a rhythmic manner. OsHAPL1 can physically interact with Days To Heading on chromosome 8 (DTH8), which physically interacts with Heading date 1 (Hd1) both in vitro and in vivo. OsHAPL1 forms a complex with DTH8 and Hd1 in Escherichia coli. OsHAPL1, DTH8, and Hd1 physically interact with the HAP complex, and also with general transcription factors in yeast (Saccharomyces cerevisiae). Further studies showed that OsHAPL1 represses the expression of the florigen genes and FLOWERING LOCUS T 1 (RFT1) and Hd3a through Early heading date 1 (Ehd1). We propose that OsHAPL1 functions as a transcriptional regulator and, together with DTH8, Hd1, the HAP complex, and general transcription factors, regulates the expression of target genes and then affects heading date by influencing the expression of Hd3a and RFT1 through Ehd1.
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